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Although there are reports that long-term blood glucose variability is a risk factor associated with osteoporosis , no previous studies have explored the relationship between blood glucose variability and fractures in non- diabetic patients
.
Recently, an authoritative journal in the field of endocrine and metabolic diseases published a research article in the Journal of Clinical Endocrinology & Metabolism.
Researchers aimed to evaluate the inter-follow-up variability (FPG) of fasting blood glucose as a predictor of the prognosis of osteoporotic fractures in non-diabetic individuals.
The effectiveness of the factor
.
Researchers used a national cohort database to assess the impact of FPG on the development of osteoporotic fractures in men and women (age ≥50 years)
.
The main outcome of the study was the total number of fractures and the number of vertebral fractures
Of the 92929 participants, 5262 (5.
7%) had an osteoporotic fracture during an average follow-up of 8.
4 years
.
After adjusting for average FPG and other risk factors, individuals with FPG-SD in the top quartile had a 11% and 16% increase in total fracture and vertebral fracture risk compared with individuals in the bottom quartile
It can be seen that FPG variants may be a new risk factor for osteoporotic fractures, independent of the risk factors for the general population
FPG variants may be a new risk factor for osteoporotic fractures, independent of the risk factors of the general population
Original source:
Original source:Jung A Kim.
Association between Visit-to-Visit Fasting Plasma Glucose Variability and Osteoporotic Fractures in nondiabetic subjects in this message
