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Thyroid dysfunction is associated with a higher prevalence of anemia, but the causal relationship is not yet clear
.
Recently, the Journal of Clinical Endocrinology & Metabolism, an authoritative journal in the field of endocrine and metabolic diseases, published a research article aimed at exploring the relationship between thyroid function and anemia
The study included a cross-sectional and Mendelian randomization study.
There were 445,482 participants with an average age of 56.
77 years (SD 8.
0), and 54.
2% were women
.
21860 (4.
The main outcome indicator of the study was anemia, which was defined as male hemoglobin level <13g/dL and female hemoglobin level <12g/dL
.
In the study, 18717 (4.
2%) participants had anemia
Although self-reported hypothyroidism is associated with a higher risk of anemia, there is no evidence to support a causal relationship with variations in thyroid function within the normal range of thyroid function
Original source:
Nicolien A van Vliet.
et al.
Thyroid function and risk of anemia: a multivariable-adjusted and Mendelian Randomization analysis in the UK Biobank .
JCEM.
2021.
https://doi.
Thyroid function and risk of anemia: a multivariable-adjusted and Mendelian Randomization analysis in the UK Biobank in this message
