JCSM: The characteristics of body composition changes in elderly patients with type 2 diabetes and prediabetes compared with controls

Background: Aging is accompanied by loss of muscle and gain of fat, which may increase the risk of type 2 diabetes (T2D)
.

However, there are few data on the local distribution of lean and adipose tissue in older adults with T2D or prediabetes compared with healthy controls

Aging is accompanied by loss of muscle and gain of fat, which may increase the risk of type 2 diabetes (T2D)

Results: The T2D group was 72±8 years old (mean±SD), dominated by males (n=1.
5/18, 83%), and overweight (BMI: 27.
8±4.
2 kg/m2, 33.
2±5.
3% body fat)
.

Compared with the HM group, upper arm lean body mass increased by 0.

Figure 1 DXA area analysis
.

The yellow lines indicate the boundaries between the head, torso (including spine and pelvis), left and right arms, and left and right legs

Figure 1 DXA area analysis

Figure 2 Placement of ImageJ measurement tools for ultrasound thickness (A, B) and muscle mass (C, D) analysis
.

The green line indicates where the thickness of the anterior thigh and abdominal muscles was measured; the blue arrows indicate where the thickness of the anterior thigh and abdominal SAT was measured

Figure 2 Placement of ImageJ measurement tools for ultrasound thickness (A, B) and muscle mass (C, D) analysis

Table 1 Composition of DXA regional institutions

Table 1 Composition of DXA regional institutions

Table 2 Ultrasound measurements of muscle and SAT thickness

Table 2 Ultrasound measurements of muscle and SAT thickness

Table 3 Ultrasound-based muscle texture features

Table 3 Ultrasound-based muscle texture features

Table 4 Physical function, strength and metabolite sub-analysis

Table 4 Physical function, strength and metabolite sub-analysis

Figure 3.
Ultrasound-based muscle texture features correlated with muscle strength (A, B) and circulating metabolic markers (C, D)
.

Two-tailed Pearson correlation analysis was performed on all participants in the same group (n=24)

Figure 3.

Our findings suggest a new body composition phenotype that is specific to older adults with T2D or prediabetes

Altered features of body composition in older adults with type 2 diabetes and prediabetes compared with matched controls.
Leave a comment here