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JGG: Carrageenan-degrading bacteria isolated from the intestine can aggravate intestinal inflammation in sterile mice

 Last Update: 2021-08-26
 Source: Internet
 Author: User

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Carrageenan CGN is a hydrophilic colloid extracted from marine red algae seaweed.

Thin layer chromatography shows that high molecular weight CGN (≥100KD) cannot be degraded by human fecal microorganisms, while low molecular weight CGNs, namely κ-carrageenan oligosaccharides (KCO, ~4.

immunity

Therefore, KCO degrading bacteria and KCO products can promote inflammation in mice, and can be used as two key markers for evaluating the safety of CGN in food and drugs

Original source: Yin, Y.

Original source: Carrageenan oligosaccharides and associated carrageenan-degrading bacteria induce intestinal inflammation in germ-free mice

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