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    Home > Active Ingredient News > Digestive System Information > JGH: Independent predictors of high-grade superficial non-ampullary duodenal epithelial tumors are tumor location and size

    JGH: Independent predictors of high-grade superficial non-ampullary duodenal epithelial tumors are tumor location and size

    • Last Update: 2021-06-21
    • Source: Internet
    • Author: User
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    With the continuous advancement of endoscopy technology and diagnosis , researchers have realized that the incidence of superficial non-ampullary duodenal epithelial tumors (SNADET) has been increasing
    .


    However, the clinical features of SNADET with malignant potential remain unclear


    With the continuous advancement of endoscopy technology and diagnosis , researchers have realized that the incidence of superficial non-ampullary duodenal epithelial tumors (SNADET) has been increasing


     

    The researchers identified 328 SNALET cases that were resected endoscopically or surgically from January 2013 to April 2019 from the endoscopy and pathology database
    .


    Then the clinical characteristics of these patients' low-grade mucosal tumors (n = 154) and high-grade mucosal tumors/submucosal carcinoma (HGN/SMC, n = 174) were compared


     

    The analysis of the study results showed that in univariate analysis, tumor size, preampullary tumor location, red color and rough/nodular surface were significantly correlated with HGN/SMC
    .


    In the multivariate analysis, tumor size (≥10 mm) (OR: 4.


     

    This study confirmed that the anterior ampullary position and the size of the large tumor are independent predictors of HGN/SMC type SNAET
    .


    The location of the preampullary tumor is significantly related to the gastric histological phenotype


    This study confirmed that the anterior ampullary position and the size of the large tumor are independent predictors of HGN/SMC type SNAET


     

    Original source:

    Katsunori Matsueda.


    Pre-ampullary location and size ≥10 mm are independent predictors for high-grade superficial non-ampullary duodenal epithelial tumors.
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