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Acute chronic liver failure (ACLF) is an acute condition with high morbidity and mortality
.
Even without systemic inflammatory response syndrome (SIRS), the 28-day mortality rate can still be as high as 6-18%
.
Acute chronic liver failure (ACLF) is an acute condition with high morbidity and mortality
In this study, 90 ACLF patients were randomly assigned to three groups: A: did not receive lipid emulsion, B: received omega-6 fatty acids, and C: received omega-3 fatty acids
.
immunity
In ACLF patients treated with omega-3 fatty acids, serum endotoxin levels were suppressed by 22%
.
And A: no lipid emulsion and B: patients who received omega-6 fatty acids increased endotoxin by 4% and 12%, respectively (P<0.
001)
+ +
This study confirmed that Omega-3 FA can safely and effectively reduce systemic inflammation, endotoxemia and sepsis in ACLF patients
.
These lipid emulsions can also be considered as an effective source of immunonutrition for such patients
.
This study confirmed that Omega-3 FA can safely and effectively reduce systemic inflammation, endotoxemia and sepsis in ACLF patients
Original source:
Anand V Kulkarni.
Et al.
Omega-3 fatty acid lipid emulsions are safe and effective in reducing endotoxemia and sepsis in acute-on-chronic liver failure: An open-label randomized controlled trial.
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