Jiao Yang, Fu Zhenhong, etc., Military General Hospital: Evaluation of serum uric acid on the prognosis of elderly patients with acute coronary syndrome with diabetes: a prospective cohort study

Content Introduction Chinese Abstract: Objective: To evaluate the predictive ability of serum uric acid level in the long-term prognosis of elderly patients with acute coronary syndrome (ACS) with diabetes
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Innovation point: For the first time to explore the predictive ability of serum uric acid level on the long-term prognosis of the specific population of elderly ACS with diabetes
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Methods: 718 patients with ACS over 80 years old who were admitted to the Heart Center of the Chinese People's Liberation Army General Hospital from January 2006 to December 2012 were selected, and general clinical data and baseline blood biochemical indicators were collected at the time of admission
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According to whether the patients have diabetes mellitus, they are grouped and followed up for long-term.
All-cause deaths and major adverse cardiac events (MACE) of the patients are recorded
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Kaplan-Meier method was used to analyze MACE incidence and all-cause mortality; multivariate Cox regression was used to analyze the relationship between serum uric acid level and long-term clinical prognosis; receiver operating characteristic curve was analyzed to predict serum uric acid in elderly patients with ACS with diabetes Diagnostic threshold
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Conclusion: The baseline serum uric acid level is an independent predictor of long-term all-cause mortality and MACE in elderly ACS patients with diabetes
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Key words: uric acid; elderly patients; acute coronary syndrome; diabetes; prognosis Authors: Yang JIAO, Jihang WANG, Xia YANG, Mingzhi SHEN, Hao XUE, Jun GUO, Wei DONG, Yundai CHEN, Qing XI, Zhenhong FU Format: Yang JIAO, Jihang WANG, Xia YANG, Mingzhi SHEN, Hao XUE, Jun GUO, Wei DONG, Yundai CHEN, Qing XI, Zhenhong FU.
Evaluation of the prognostic ability of serum uric acid for elderly acute coronary syndrome patients with diabetes mellitus : a prospective cohort study[J].
Journal of Zhejiang University Science B, 2021, 22(10): 856-865.
http://doi.
org/10.
1631/jzus.
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