Grand Medicine is expected to win the first imitation of Cinacalcet Hydrochloride

[January 13, 2019 / medical information list] the opinion draft of technical guidelines for research on nitroamine impurities in chemical drugs was released; in 2019, the cancer field fell to the top of round a financing market, and the IPO market continued to heat up; the first mRNA vaccine entering phase 2 clinical research is expected to reduce congenital defects Daily fresh medicine news, speed reading club and you pay attention to! Recently, the national medical security working conference was held in Beijing The meeting summarized the medical security work in 2019, and studied and deployed the key tasks of medical security in 2020 According to reports, the State Council will formulate policies for the future national centralized mining plan, and the National Health Insurance Bureau will carry out specific implementation The goal is to make the top 160 varieties of hospital procurement amount from high to low as the focus of future centralized procurement It is planned to carry out another three years and make another 5-6 batches (people's network) On January 13, Shandong Medical Insurance Bureau issued the notice on carrying out the renewal work of drug contract negotiation in Shandong Province, encouraging the renewal enterprises of five major varieties such as enacep for injection and the newly listed similar drugs to voluntarily declare and negotiate (medicine cube) Recently, FDA announced three recall announcements of ranitidine in a row, and the problem of nitrosamine impurity was pushed to the air outlet On January 10, the State Food and Drug Administration issued the technical guidelines for the study of nitrosamine impurities in chemical drugs (Draft for comments) Recently, the famous Silicon Valley Bank released its investment and financing report for the whole year of 2019 The annual investment and financing report "healthcare investments & exits" points out that the financing of U.S venture capital institutions focused on health care reached $10.7 billion in 2019, a record for the third consecutive year In the field of biomedicine, IPO market is extremely hot (chuangjianhui) Asia Pacific pharmaceutical disclosed the announcement on the freezing of the company's bank accounts on January 11 As of January 10, 2020, three bank accounts of the company had been frozen, with a total frozen amount of 104.3673 million yuan On December 12, the Asia Pacific pharmaceutical industry released a supplementary announcement on the freezing of the company's bank account (Sina Medical News) On December 12, Zejing pharmaceutical released the initial public offering of shares and listed them on the science and technology innovation board According to the announcement, the issue price was determined to be 33.76 yuan / share through negotiation, and subscription was started on the 14th The total scale of this issuance is 2.026 billion yuan, and the market value of the company corresponding to this price is 8.102 billion yuan (Sina Medical News) On January 13, Yuheng pharmaceutical announced that it had signed an intentional termination agreement with biotons A and scigen PTE Ltd on January 10 to terminate the supply and marketing agreement related to the exclusive sales rights of Protamine Insulin Injection, Protamine Insulin premixed injection and other products in China (medicine cube) A few days ago, Moderna company announced that its research cytomegalovirus vaccine (mrna-1647) in phase I clinical research, after the third vaccination, obtained 7 months of safety and immunogenicity positive results in the medium term At the same time, Moderna announced that the phase 2 dose confirmation study had been administered to the first subject (yaomingkant) Cornerstone pharmaceutical and blueprint medicine jointly announced the launch of their PD-L1 inhibitor cs1001 and fisogatinib in the treatment of locally advanced and metastatic HCC patients in phase 1B / 2 clinical trials, to evaluate the antitumor activity of targeted therapy and cancer immunotherapy in locally advanced and metastatic HCC patients At present, both parties have completed the first patient administration of the trial (yaomingkant) At present, the listing application of 4 kinds of generic drugs of sinakase hydrochloride tablets of Jiayi pharmaceutical is "under review and approval" As the only enterprise in China whose generic drug listing application of sinakase hydrochloride tablets has been included in the priority review list, Jiayi pharmaceutical is expected to take the lead in obtaining the first generic drug of sinakase and compete with the original research drug Geping (CPHI Pharma online) On the 13th, Cinda biology and Lilly pharmaceutical jointly announced that the combination of PD-1 inhibitor Dabusu ® (cindilimab injection) and chemotherapy in the first-line treatment of non squamous non-small cell lung cancer reached the main research end point in phase 3 clinical (Sina Medical News) Recently, akari therapeutics released positive interim data of C5 complement inhibitor nomacopan in the treatment of paroxysmal nocturnal hemoglobinuria (PNH) phase III capstone study (Sina Medical News) According to the latest data of minenet, edaravone sodium chloride injection class 3 generic listing application of Jiangsu zhengdafenghai pharmaceutical, affiliated to China biopharmaceutical, has been approved, and has successfully become the first generic in China The approval of registration according to the new classification is deemed to pass the consistency evaluation (meter net) According to the announcement released on November 11 by Lu Kang pharmaceutical, the approval document for drug registration of calcium acetate granules issued by the State Food and drug administration has been received At present, there are Kunming BANGYU Pharmaceutical Co., Ltd and Henan Nome Pharmaceutical Co., Ltd approved to produce calcium acetate granules in China, which is the third approved company (meter net) Jichuan pharmaceutical, a subsidiary of the company, received the approval document for drug registration for levolacetam concentrated solution for injection approved and issued by the State Food and drug administration, the company announced Tuesday (Sina Medical News) Recently, in a research report published in the International Journal chemmed Chem, scientists from the University of bath and other institutions in the UK developed a drug like molecule inspired by a special compound in tropical flowers, which may help to treat deadly pancreatic cancer (Biovalley) Recently, in a research report published in the international journal Proceedings of the National Academy of Sciences, scientists from New York City University and other institutions have studied or are expected to help develop new drugs for the treatment of Clostridium difficile infection (Biovalley)