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    Home > Active Ingredient News > Antitumor Therapy > JNCCN: Transanorectal total mesangial resection (TaTME) for the treatment of local recurrence and disease-free survival of rectal cancer: results from the international TaTME registration study

    JNCCN: Transanorectal total mesangial resection (TaTME) for the treatment of local recurrence and disease-free survival of rectal cancer: results from the international TaTME registration study

    • Last Update: 2021-09-12
    • Source: Internet
    • Author: User
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    The oncological safety of transanorectal total mesangial resection (TaTME) for the treatment of rectal cancer has recently been questioned, and a high local recurrence rate (LR) has been reported in clinical practice in the Netherlands and Norway


    The oncological safety of transanorectal total mesangial resection (TaTME) for the treatment of rectal cancer has recently been questioned, and a high local recurrence rate (LR) has been reported in clinical practice in the Netherlands and Norway


    This is a prospective internationally registered cohort study, including all patients with primary rectal adenocarcinoma treated with TaTME from February 2010 to December 2018


    This is a prospective internationally registered cohort study, including all patients with primary rectal adenocarcinoma treated with TaTME from February 2010 to December 2018


    After a median follow-up of 24 months (IQR, 12-38 months), the 2-year LR rate was 4.



    LR rate

    Multivariate Cox regression analysis showed that the independent risk factor for LR was male (OR, 1.


    Multivariate Cox regression analysis showed that the independent risk factor for LR was male (OR, 1.



    LR related factors

    The 2-year DFS rate was 76.


    The 2-year DFS rate was 76.



    DFS rate

    The 2-year OS rate was 91.


    The 2-year OS rate was 91.



    OS rate

    In summary, the study shows that the transanorectal total mesangectomy (TaTME) treatment of rectal cancer has an acceptable LR rate


    In summary, the study shows that the transanorectal total mesangectomy (TaTME) treatment of rectal cancer has an acceptable LR rate
    .
    This study shows that the transanorectal total mesangectomy (TaTME) treatment of rectal cancer has an acceptable LR rate
    .
    This study shows that the transanorectal total mesangectomy (TaTME) treatment of rectal cancer has an acceptable LR rate
    .

    Original source:

    Original source:

    Sapho X.
    Roodbeen, Marta Penna, MBBS, Susan van Dieren, et al.
    Local Recurrence and Disease-Free Survival After Transanal Total Mesorectal Excision: Results From the International TaTME Registry.
    J Natl Compr Canc Netw, doi: 10.
    6004/jnccn.
    2021.
    7012 .
    Published online August 17, 2021.

    Sapho X.
    Roodbeen, Marta Penna, MBBS, Susan van Dieren, et al.
    Local Recurrence and Disease-Free Survival After Transanal Total Mesorectal Excision: Results From the International TaTME Registry.
    J Natl Compr Canc Netw, doi: 10.
    6004/jnccn.
    2021.
    7012 .
    Published online August 17, 2021.


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