JNNP: Effects of coronavirus COVID-19 on long-term hospitalized neurologic patients.

THE SARS-CoV-2, which broke out in late February, struck Italy and quickly spread from Lombardo to other parts of Italy, with more than 31,000 deaths.
, although COVID-19 patients are reported in all regions, the eastern province of Lombardo has the highest number of confirmed cases.
cases and small series of studies have also shown a link between COVID-19 and cerebrovascular disease, including immune or inflammatory-mediated peripheral and central nervous systems (CNS).
has yet to report a large-scale comprehensive report on the effects of COVID-19 on neurological conditions in emergency patients.
fact, little is known about the most common acute neurological manifestations of COVID-19 and whether there is a difference in severity and prognosis between these diseases and those without COVID-19.
the purpose of this study was to study the effects of COVID-19 by recording clinical manifestations, laboratory characteristics, and treatment/results of a range of nervous system patients who continued to appear in emergency rooms (EDs) during peak epidemic periods.
study was conducted at a third-level referral neurology center.
: From 20 February to 30 April 2020, 550 adult patients with neurological symptoms were assessed in the emergency room.
147 (29.1%) of these cases tested positive for SARS-CoV-2.
patients with COVID-19 were significantly older (73.1±12.4 years vs. 65.1±18.9 years, p.0. 001), the distribution of nervous system manifestations is also different (p-0.001), mental state changes or delirium is more frequent (25.9% to 10.1%), but seizures and headache/pain are less frequent (see Table 1) for details.
the final diagnosis, patients with COVID-19 positive had a higher prevalence of ischemic stroke (n=51,34.7%vs n=105,29.3%), delirium (n) 24,16.3% vs n=18,5.0%) and meningitis/encephalitis (n=14,9.5%vs n=7,1.9%).
laboratory analysis of patients who tested positive for COVID-19 showed elevated serological levels of C-reactive proteins, tyrosine and alanine transaminase and fibrinogens (p-lt;0.05).
patients with COVID-19 had higher hospitalization rates after ED division (91.2% to 69.3%, p.lt;0.0001) and hospitalization mortality rates (29.7% to 3.1%, p.lt;0.0001).
, cerebral hemorrhage (ICH) (COVID-19 positive 58.3%, non-COVID-19 33.0%), ischemic stroke (COVID-19) Positive 39.2%, non-COVID-19 2.8%) and mental disorder/mental state change (COVID-19 positive 23.4%, non-COVID 0%) mortality rate was higher.
in COVID-19, mortality is associated with old age and co-merger.
coronavirus has associated effects on neurological performance and health status, as patients with the nervous system require more frequent hospitalization and are at higher risk of mortality and disability upon discharge.
need further research to compare different care patterns to determine the most effective tissue to counteract the effects of COVID-19 on patients with the nervous system.
Pilotto A, Benussi A, Libri I, et al COVID-19 impact on on-run neurological patients admitted to the emergency department Journal of Neurology, Neurosurgery and Psychic Published Online First: 14 October 2020. doi: 10.1136/jnnp-2020-323929MedSci Original Source: MedSci Original Copyright Notice: All text, images and audio and video materials on this website that indicate "Source: Met Medical" or "Source: MedSci Original" are owned by Mets Medicine and are not authorized to be reproduced by any media, website or individual. Source: Mays Medicine.
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