-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects motor neurons and causes paralysis of skeletal muscles, including respiratory muscles
.
The etiology of amyotrophic lateral sclerosis is still unclear, and it is likely to be multifactorial
(Energy expenditure at rest) REE is the energy required to maintain the integrity and function of cells, tissues, organs and systems under basic conditions
.
REE is the most important part of TEE, besides it also includes the energy expenditure of physical activity and diet-induced thermogenesis
The mREE and TEE values of ALS patients are still widely controversial
.
Especially the mREE of ALS patients has severe changes (high metabolism) in the relevant percentage of patients
The literature currently lacks information on the existence and consequences of hypometabolism in ALS patients
This retrospective study included a group of consecutive patients who were subjected to indirect calorimetry to determine the metabolism of ALS patients between January 2011 and December 2017
.
The patient was admitted to the hospital and followed up regularly
According to REE, the demographic and clinical characteristics of the cohort
Anthropometric parameters for measuring weight and height
.
Use a mechanical scale to measure your weight
Draw a Kaplan-Meier survival curve based on metabolic status
In addition, patients should avoid drinking caffeinated beverages or smoking before the examination
.
Before starting the measurement, ask the patient to lie on the bed for 10-20 minutes while waiting for the instrument to be recalibrated
[(mREE−cREE)/cREE]×100 ≥10% and hypometabolism as [(mREE−cREE)/cREE]×100 ≥−10%
This study included 847 ALS patients with a median age of onset of 63.
In conclusion, low metabolism of ALS is not uncommon.
Compared with subjects with normal metabolism and high metabolism, low metabolism is associated with slower disease progression and better survival
.
Compared with subjects with normal metabolism and high metabolism, low metabolism is associated with slower disease progression and better survival
.
In conclusion, low metabolism of ALS is not uncommon.
Compared with subjects with normal metabolism and high metabolism, low metabolism is associated with slower disease progression and better survival
.
CattaneoM ,JesusP , Lizio A Cattaneo M Cattaneo Jesus P Jesus Lizio A Lizio , et al The hypometabolic state: a good predictor of a better prognosis in amyotrophic lateral sclerosis Journal of Neurology, Neurosurgery & Psychiatry Published Online First: 05 August 2021.
Published Online First: doi: 10.
1136/jnnp-2021-326184 doi:
Leave a message here
