JNNP: ISE stroke associated with COVID-19: Is there a specific pattern?

COVID-19 can cause serious respiratory diseases and is associated with isoemia stroke (Is).
the purpose of this study was to describe the characteristics of PATIENT and COVID-19 patients, compare them with COVID-19, negative IS patients treated at the same time, and try to identify specific patterns of IS in COVID-19.
between March 20 and April 20, 2020, the authors conducted the comparative study at two hospitals.
and control groups were adult patients who had recently been hospitalized, confirmed by neuroimaging.
if SARS-CoV-2's nasopharyngeal reverse transcription (RT-PCR) test is positive and/or chest CT scans are typical of COVID-19, they are diagnosed with COVID-19.
exclusion criteria are transient isoemia attacks, hemorrhagic strokes, or strokes that are followed by venous thrombosis in the brain.
collected demographic data, cardiovascular risk factors, neurological data, blood test results, hospitalization and discharge results.
reviewed the available test results for each patient (vascular imaging and cardiac assessment of the arteries of the brain and neck, including 12-conducting electroeniograms, 48-hour continuous electroeniogram monitoring and thoracic echo cardiacgrams), based on astro-astrophic acid types (a: a: atherosclerosis; S: small vascular disease; C: cardiology; O: other causes; D: anatomy).
Fisher precision test and Wilcoxon-Mann-Whitney test compared the classification and continuous variables of the case group and the control group, respectively.
statistical significantness is defined by the P-value of 0.05.
67 IS patients were admitted to hospital (41 at Pitti-Sapit-Erel Hospital and 26 at St. Anthony's Hospital).
, 12 (17.9%) of them were infected with SARS Cov-2.
41.7% of COVID-19 patients had a stroke.
for other COVID-19 IS patients, the average delay between initial COVID-19 symptoms and stroke imaging was 17 days.
the coVID-19 lung severity was mild, only two patients needed more than 6 L/min of additional oxygen, and none developed acute respiratory distress syndrome.
the proportion of patients under 60 years of age in coVID-19 patients and the proportion of patients of Afro-Caribbean descent (p=0.008).
although none of the patients with COVID-19 had multiple cerebral vascular throesosis, the severity of stroke in the case group tended to be higher near-end arterial throes (p=0.053).
in patients with COVID-19, abnormal symptoms such as delirium or apathy are more common.
in patients with COVID-19 who showed delirium, there were two cases ofsmall infarction, one of which had mild lymphocytic meningitis.
cause of
S (atherosclerosis thrombosis and cerebrovascular disease) was significantly higher in the COVID-19 group (58.3%, n=7/12) than in the control group (27.3%, n=15/55) (p=0.049).
41.7% of cases had underlying atherosclerosis thrombosis, compared with 20.4% in the control group.
the North American symptomatic cervical artery endometriosis trial classification, in 5 cases of COVID-19 patients, 4 cases of convective cervical artery stenosis degree is higher than 50%.
fifth patient had floating blood clots in the aortic bow, accompanied by atherosclerotic plaques less than 4 mm, which required further more validation studies to confirm the findings because of the small sample size.
Januel E, Bottin L, Yger M, et al Ischaemic strokes associated with COVID-19: is there a specific pattern? Journal of Neurology, Neurosurgery and Psython Published Online First: 29 October 2020. doi: 10.1136/jnnp-2020-323942MedSci Original Source: MedSci Original Copyright Notice: All notes on this website "Source: Met Medical" or "Source: MedSci Original" text, images and audio and video materials, copyrights are owned by Metz Medicine, without authorization, no media, website or individual may reproduce, authorized to reproduce with the words "Source: Mets Medicine".
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