JPD: The higher the level of education, the better the prognosis of Parkinson's patients with motor symptoms

The concept of cognitive reserve (CR) explains the differences in susceptibility to Alzheimer's disease (AD)-related conditions between individuals

Parkinson's disease (PD) is a popular neurodegenerative disease that affects the elderly and brings significant motor compensation

In this way, Seong Ho Jeonga of Korea University and others explored the effect of pre-ill education on the prognosis of PD in long-term exercise, such as the development of LID and FOG, and the increase of LEDs

They analyzed 466 new-onset Parkinson's disease patients without dementia who underwent a dopamine transporter (DAT) scan and followed up for more than 2 years

The patients were divided into three groups: low education (years of education ≤ 6 years, n=125)

The effect of education level on development The effect of education level on levodopa-induced dyskinesia (LID), regression and gait freezing

They found that after adjusting the availability of DAT, higher education was associated with milder Parkinson's disease symptoms

The linear mixed model showed that the LED of the high-educated group was lower than that of the low-educated group until 30 months; however, this LED difference was not observed afterwards

The study shows that the level of education before illness has a protective effect on the development of LID in PD patients