Kamasipine can cause deadly skin reactions
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Last Update: 2020-07-05
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Source: Internet
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Author: User
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the FDA recently notified medical staff that the use of carbamazepine can lead to dangerous and even fatal skin reactions (Stevens Johnson syndrome and toxic epidermal necrosis laxism), and is more common in patients with specific human leukocyte antigen (HLA) allele HLA-B-1502These bits are found almost exclusively in patients with Asian origin, including India in South AsiaIf the patient has the lineage of hlA-B x 1502 endemic areas, the HLA-B x 1502 allele should be screened before starting kamapine treatmentIf the test results are positive, cannot use kamasipine unless the benefits of treatment clearly outweigh the risk of severe skin reactionIf the patient has been using kamasipine for several months and there is no skin reaction, the risk of karmasi skin reaction is reduced, which applies to patients of any race or genotype, including those who are HLA-B x 1502 positive
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