Laboratory pelletizer is a necessary equipment in pharmaceutical industry

Laboratory dry granulator is a dry granulator developed by our company It is a small Zui dry granulator for laboratory research and development It is suitable for laboratory, intermediate experimental device and small production It only needs about 80g dry powder to form According to the principle of mechanical extrusion granulation process, the prepared dry powder or micro crystal raw materials with a certain amount of crystal water are extruded into thin sheets, and then through the granulation system, the required size particles are made through the screen The raw materials can be fed into the hopper by manual or vacuum feeding machine, transported and compressed by the vertical feeding screw, and pushed to the biting angle of the two extrusion roller wheels; the raw materials can be extruded into thin sheets by the horizontal pressing roller (the speed of the pressing roller determines the residence time of the materials in the roller pressing area); the required pressure of the materials is transmitted to the pressing roller linearly by the hydraulic device, and the vertically arranged pressing roller can be guaranteed Verify consistency of material density The machine is easy to install, disassemble and clean According to different particle size requirements, the mesh size of the equipment granulation system can be changed mutually The raw materials of powder are directly made into granular products that meet the requirements of users without any intermediate and additive After granulation, the particle size of the products is uniform, the stacking density is significantly increased, the fluidity is improved, the flying dust is controlled, the waste of powder is reduced, the storage and transportation are convenient, and the solubility, porosity and specific surface area are controlled It can be directly used for tablet pressing or capsule filling It is especially suitable for granulating drugs which can not be pelletized in traditional wet granulation and are not stable in hot and humid conditions Dry granulation process can replace the investment of wet granulation line and save manpower, material and financial resources It is a new energy-saving and environmental protection equipment It can be widely used in pharmaceutical, food, chemical and other industries Jito is a high-tech equipment manufacturing enterprise which introduces foreign technology, domestic research and development, advanced manufacturing technology, production and sales So what role does equipment play in the pharmaceutical industry? Equipment is the key equipment in pharmaceutical production Its function and configuration directly determine the value of the production line Under the same formula and technology, whoever can improve the comprehensive efficiency of the laboratory pelletizer will win direct economic benefits for the factory Therefore, how to let the laboratory dry granulator play the big function of Zui, reduce the production cost of tons of materials, improve the output and quality, is a problem that every manufacturer needs to solve The key functions of the equipment are mainly reflected in the following aspects: 1 It can adapt to the pelletizing requirements of different materials and different formulas when equipped with corresponding processing technology (tempering temperature, moisture, compression ratio of ring mold); 2 Under the same formula and specification, the granulator has high output, low powder ratio, good appearance quality (incision rate, uniform thickness and length), good stability and effect; 2 The granulator has stable operation, safe and reliable operation, sanitary sealing of each interface, low failure rate, long working time of the ring molding roller; high degree of automation and convenient maintenance In the pharmaceutical industry, the dry granulation machine is an important machine to make the dry powder into particles Due to the continuous improvement of GMP standard, the dry granulation process is also attached great importance to by the pharmaceutical industry, and it is required to meet the requirements of energy conservation and environmental protection According to experts, dry granulation is a new Zui granulation method developed after the second generation of granulation method "one step granulation" It is a kind of environmental protection granulation process, energy-saving and pollution-free, without wetting agent (solvent alcohol, water and starch pulp, etc.), explosion-proof problem of solvent-free granulation and environmental protection problem of waste gas emission pollution; it saves the drying process and saves a lot of energy; with the continuous development of new adhesives for dry granulation, the cost of dry granulation is greatly reduced Automatic technology promotes the development of dry granulation technology, and the automatic dry granulation machine emerges as the times require At present, it has been widely used in pharmaceutical, food, chemical industry and other industries in China, especially for the granulation of drugs that are easy to decompose, absorb moisture and sensitive to heat Its particles can be used to increase density and improve fluidity, tablet pressing, filling capsules and granule bagging Based on many advantages, it is widely used in various industries The above is about the laboratory dry granulation machine is the necessary equipment of the pharmaceutical industry I hope it can help me to understand this equipment.