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    Home > Medical News > Medical Research Articles > labrasol [Surfactant] Caprylic acid capric acid polyethylene glycol glyceride (EP)

    labrasol [Surfactant] Caprylic acid capric acid polyethylene glycol glyceride (EP)

    • Last Update: 2021-07-29
    • Source: Internet
    • Author: User
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    labrasol [Surfactant]

    Chemical name : Caprylic acid capric acid polyethylene glycol glyceride (EP)

    English name : Caprylocaproyl Macrogolglycerides

    Application : Non-ionic amphiphilic excipients with high HLB value
    .

            As a bioavailability promoter and solubilizer in oral liquid and solid prescriptions of poorly soluble drugs;

            As a penetration enhancer in topical administration;

            Used as a surfactant in microemulsion
    .

    Appearance : oily liquid

    HLB value : 14

    Solubility at 20°C (European Pharmacopoeia third edition):

                   Easily soluble in 96% alcohol

                   Easily soluble in chloroform and dichloromethane

                   Soluble in water

                   Insoluble in mineral oil

    Toxicology : Oral acute toxicity (100%) (rat/LD 50 =22g/kg): non-toxic
    .

          Basic skin irritation (100%): very well tolerated
    .

          Eye irritation (100%): Slight irritation
    .

          Acute skin toxicity (100%): Very well tolerated
    .

          Bacterial reverse mutation test (Ames test): no mutagenic substances
    .

    Regulatory status : (1) USP-NF/EP/IIG

              (2) Import registration certificate number: H20052377

    Packing : 25kg/drum, 200kg/drum

    Storage : Store in a cool and dry place, avoid exposure to air

     

    Supplier: Jiafa Shi

    Contact: Manager Liu

    Contact number: 139 1173 0390

    E-mail: eileenliu@gattefossecn.
    com

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