Lancet Gastroen Hepatol: HCV Risk Study of Male Behavioral Groups

Male Behavioral Population (MSM) is a high-risk group for the spread of hepatitis C virus (HCV), and researchers recently conducted a systematic review and meta-analysis to examine the prevalence and incidence of HCV in the MSM population.
researchers conducted a systematic review and meta-analysis of the studies published on MEDLINE or Embase between 1 January 2000 and 31 October 2019, including the minutes of the meeting.
met the requirements of the study showed the prevalence of HCV or the incidence of HCV in MSM (or both).
194 studies were included in this systematic review and meta-analysis.
, the combined HCV prevalence rate for the MSM population was 3.4 per cent, with Africa (5.8 per cent) and South-East Asia (5.0 per cent) the highest.
, the prevalence of HCV was 1.5% among HIV-negative MSM populations and 6.3% among HIV-positive people.
HIV-negative MSM population had slightly higher prevalence of HCV compared with the general population, and HIV-positive MSM population increased significantly.
the prevalence of HCV was significantly higher in MSM populations who had been injected with drugs (30.2%) or were currently injecting drugs (45.6%), the prevalence of HCV was significantly higher than in those who had never injected drugs (2.7%).
in HIV-negative MSM, the combined incidence of HCV in non-AIDS pre-exposure prevention (PrEP) individuals was 0.12/1000 years, and in PrEP individuals it was 14.80/1000 years.
hiv-positive MSM, the incidence of HCV was 8.46/1000 people-years.
study found that HIV-positive male behavioral groups significantly increased the risk of HCV infection, and AIDS pre-exposure prevention frequency increased, the corresponding risk of HCV infection also increased significantly.