Lancet Infect Dis: It can predict the subsequent development of dengue fever into severe clinical factors in the fever period

The ability to accurately predict the progression of early dengue fever into a severe disease is essential for patient classification and clinical management .

management

This study aims to identify factors that are particularly easy to find in the fever stage associated with the development of severe dengue fever disease.

This study aims to identify factors that are particularly easy to find in the fever stage associated with the development of severe dengue fever disease.

Researchers screened data from 8 medical databases from January 1, 1997 to January 30, 2020, and used systematic reviews and meta-analysis to identify predictive factors related to the development of severe fever in the course of fever.

Screening

Of the 6643 studies screened, 150 of them were included in this systematic analysis, and 122 articles containing 25 potential predictors were included in the meta-analysis.

Factors related to development of severe illness

Factors related to development of severe illness

In the main analysis, female patients had a higher risk of developing severe dengue fever than male patients (16.

Risk female patients develop severe dengue fever higher than male patients risk female patients develop severe dengue patients than male children with severe dengue-related underlying diseases have diabetes (31.

Factors related to development of severe illness

Factors related to development of severe illness

The clinical features associated with the progression of severe disease during fever are vomiting (13.

The clinical features associated with the progression of severe disease during fever are vomiting (13.

infection

In summary, this analysis supports monitoring of the warning signs described in the 2009 WHO Dengue Fever Guidelines.

This analysis supports monitoring of the warning signs described in the 2009 WHO Dengue Fever Guidelines.

Original source:

Sorawat Sangkaew, et al.

org/10.
1016/S1473-3099(20)30601-0" target="_blank" rel="noopener">Risk predictors of progression to severe disease during the febrile phase of dengue: a systematic review and meta-analysis in this message