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If the carotid artery that supplies the brain is compared to the crown of a tree, water is transported to each leaf through the branches from thick to thin, and the last branch is the "small cerebral blood vessel .
If the carotid artery that supplies the brain is compared to the crown of a tree, water is transported to each leaf through the branches from thick to thin, and the blood vessels
In a broad sense, small blood vessels in the brain refer to blood vessels in the deep part of the cerebral cortex with a diameter of less than 500 μm.
Small blood vessels in the brain specifically refer to small blood vessels with a diameter of less than 200μm in the brain, whose thickness is equivalent to a few hair strands.
In many cases, CSVD does not have obvious symptoms.
In many cases, CSVD has no obvious symptoms.
CSVD CSVD is also the most common main cause of vascular dementia in the world .
In this analysis, the researchers searched MEDLINE, EMBASE, and PsycINFO for related articles published before January 24, 2020.
Among the 7119 papers screened, 81 studies (including 79 cohorts) met the inclusion criteria (n=21730 participants, average age 69-2 years).
The researchers chose the main pathological manifestation of CSVD-WMH in MRI examination to represent the severity of the disease.
The results showed that, in general, there is a close relationship between the severity of WMH and apathy (OR 1.
There is a close relationship between the severity of WMH and apathy (OR 1.
The most common symptoms of CSVD include:
1) It becomes difficult to complete some daily tasks , the reaction becomes slow, and it is easy to lose focus, etc.
1) Complete some daily tasks
2) There are some symptoms similar to normal aging, such as a different walking posture, easy falls, increased number of night visits to the toilet, or urinary incontinence, etc.
3) There are also emotional abnormalities in some patients, such as often depressed, unhappy, or always nervous, anxious, worried, etc.
3) There are also emotional abnormalities in some patients,
4) In addition, some patients with CSVD will have symptoms similar to cerebral infarction or cerebral hemorrhage, such as sudden unclear speech, or numbness and weakness on one side of the limb.
4) In addition,
For this reason, the researchers pointed out that apathy, fatigue, and delirium are closely related to the degree of WMH, and subjective cognitive decline may not be related in this study.
In summary, the comprehensive understanding of CSVD and the ability of early clinical detection should be improved to intervene the disease early in the course of the disease.
The comprehensive understanding of CSVD and the ability of early clinical detection should be improved to intervene the disease early in the course of the disease.
references:
Neuropsychiatric symptoms associated with cerebral small vessel disease: a systematic review and meta-analysis.
https://doi.
org/10.
1016/S2215-0366(20)30431-4
https://doi.
org/10.
1016/S2215-0366(20)30431-4 Neuropsychiatric symptoms associated with cerebral small vessel disease: a systematic review and meta -analysis.
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