Lancet Respiratory Medicine: One year after discharge from the new crown, more than 70% of patients still have sequelae

The new coronavirus usually infects humans through the respiratory tract and causes damage to the respiratory system and various organs of the human body

In the two years since the epidemic, we have realized that the new crown is not just a respiratory disease, but affects multiple tissues and organs of the human body

On April 23, 2022, researchers from the University of Leicester in the UK published online in The Lancet Respiratory Medicine , a sub-journal of The Lancet: Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a research paper for a prospective observational study

The Lancet Respiratory Medicine Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study

The study of more than 2,000 hospitalized patients with Covid-19 showed that only 29% of patients fully recovered after a year of infection with Covid-19, and 71% had sequelae, the most common sequelae being fatigue, muscle pain, slowing down, sleep Poor and difficult to breathe

One year after contracting Covid-19, only 29% of patients had fully recovered, and 71% had sequelae, the most common of which were fatigue, muscle pain, slowing down, poor sleep and difficulty breathing

For the study, researchers analysed patients from 39 UK National Health Service (NHS) hospitals, including 2320 adult participants discharged between March 7, 2020 and April 18, 2021 , of whom 807 Participants (32.

2320

Recovery was assessed using patient-reported outcome measures, physical performance, and organ function at 5 months and 1 year after discharge

Statistical analysis found that 25.

The proportion of patients reporting complete recovery was 25.

Recovery status of patients at 5 months and 1 year

Recovery status of patients at 5 months and 1 year

The study found that compared with men, women were 32 percent less likely to make a full recovery; those who were obese were 50 percent less likely to make a full recovery; and those who required mechanical ventilation were 58 percent less likely to make a full recovery

The results showed that being female, being obese and being mechanically ventilated in the hospital were all associated with a lower likelihood of a full recovery after one year

Comparison of patient recovery outcomes at 5 months and 1 year

Comparison of patient recovery outcomes at 5 months and 1 year

In the study, the limited recovery in symptoms, mental health, exercise capacity, organ damage and quality of life from five months to one year after hospitalization was striking, the researchers said

They also highlighted that being female and obesity were major risk factors for non-recovery after 1 year, as being female and obesity were associated with more severe ongoing health impairments, including decreased exercise performance and health-related quality of life

With a lack of treatments for COVID-19 sequelae, findings underscore the urgent need for healthcare services to support this large and rapidly growing patient population with numerous symptoms, including decreased exercise capacity and health-related quality of life a year later dropped sharply

Without effective treatments, COVID-19 sequelae could become a highly prevalent new long-term disease, researchers say

 

Original source:

Original source:

Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study .

Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study .
The Lancet Respiratory Medicine, 2022.
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