Lancet sub-journal: A large cohort of 80,000 people suggests that these 20 symptoms are red flags before Alzheimer's is diagnosed!

Identifying modifiable risk factors for Alzheimer's disease (AD) is critical for early prevention and the targeting of new interventions

Identifying modifiable risk factors for Alzheimer's disease (AD) is critical for early prevention and the targeting of new interventions

Unadjusted odds (ORs) and 95% CIs between AD and various health conditions were estimated, with P values ​​adjusted for multiple comparisons

Ten health conditions were significantly and positively associated with increased risk of Alzheimer's disease in the exposure window 2-10 years before AD diagnosis, including: 10 health conditions in the exposure window 2-10 years before AD diagnosis Health conditions are significantly positively associated with an increased risk of Alzheimer's disease, including:

Major depressive disorder (UK OR 1.

Major depressive disorder (UK OR 1.

Anxiety (UK OR 1.

Responsiveness and adjustment disorder to severe stress (UK OR 1.

Hearing loss (UK OR 1.

Constipation (UK OR 1.

Spondylosis (UK OR 1.

Abnormal weight loss (UK OR 1.

Discomfort and fatigue (UK OR 1.

Memory loss (UK OR 7.

Syncope and collapse (UK OR 1.

Depression was the first comorbidity associated with Alzheimer's disease, presenting at least nine years before the first clinical diagnosis, followed by anxiety, constipation and abnormal weight loss

In addition, symptoms including hypothyroidism, sleep disturbance, cerebrovascular disease , hypotension, inguinal hernia, back pain, other urinary system diseases, urinary incontinence, nocturia, dizziness and vertigo, forearm fractures, fractures, etc.

In addition, symptoms including hypothyroidism, sleep disturbance, cerebrovascular disease , hypotension, inguinal hernia, back pain, other urinary system diseases, urinary incontinence, nocturia, dizziness and vertigo, forearm fractures, fractures, etc.
associated with an increased risk of AD at 0-2 years
.
In addition, symptoms including hypothyroidism, sleep disturbance, cerebrovascular disease , hypotension, inguinal hernia, back pain, other urinary system diseases, urinary incontinence, nocturia, dizziness and vertigo, forearm fractures, fractures, etc.
associated with an increased risk of AD at 0-2 years
.
Blood vessel

Taken together, this study provides new evidence of potential risk factors and early signs associated with AD that can be observed in the primary care setting
.

Taken together, this study provides new evidence of potential risk factors and early signs associated with AD that can be observed in the primary care setting
.
Taken together, this study provides new evidence of potential risk factors and early signs associated with AD that can be observed in the primary care setting
.

 

references:

Identifying health conditions associated with Alzheimer's disease up to 15 years before diagnosis: an agnostic study of French and British health records.
https://doi.
org/10.
1016/S2589-7500(21)00275-2

Identifying health conditions associated with Alzheimer's disease up to 15 years before diagnosis: an agnostic study of French and British health records.
https://doi.
org/10.
1016/S2589-7500(21)00275-2

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