Lancet Sub-Journal: Disruption! The leading cause of death in diabetics is no longer cardiovascular disease!

As the population grows and ages, the number of adult diabetics worldwide has increased from 108 million in 1980 to 422 million in 2014.
diabetes poses enormous health challenges for individuals, families, social health systems and even the world economic system.
diabetes significantly increases the risk of cardiovascular conditions such as isothemia heart disease, stroke, kidney and neuropathy.
current secondary prevention of diabetics is mainly aimed at the above-mentioned complications.
, however, there is growing evidence that diseases including infections, liver disease, dementia, and certain cancers are also closely linked to diabetes.
, academic groups including the American Endocrinology Society, the American Association of Clinical Endocrinologists, and the American Gastroenterology Association issued a joint statement on the assessment and management of patients with high incidence of liver disease in T2DM patients. the
statement noted that the prevalence of fatty liver disease, advanced fibrosis and cirrhosis in patients with type 2 diabetes (T2DM) is on the rise, and that interdisciplinary collaboration to establish clinical guidelines for targeted screening and treatment is critical to prevent irreversible liver damage in patients with T2DM.
understanding the occurrence and development trends of these disease complications is of great importance to public health, prevention and improvement of clinical measures.
, a team of experts from Imperial College London followed more than 300,000 people with diabetes for 18 years to conduct a comprehensive analysis of the causes of death.
results were published in the latest Lancet Diabetes Endocrinology journal.
In this epidemiological analysis of primary care records, researchers looked at 313,907 patients registered in the Datalink Primary Care Database for clinical practice studies between 2001 and 2018 and linked the data to mortality data from the Office for National Statistics.
followed by a continuous cross-sectional study of longitudinal follow-up of diabetics.
, the overall mortality rate for men with diabetes decreased by 32 per cent and for women by 31 per cent between 2001.01.01 and 2018.10.31.
same time, non-diabetic individuals had a similar decline.
as a result, the mortality gap between diabetics and non-diabetic patients was maintained during the study period.
, the team explains, this is because deaths from cardiovascular diseases such as heart disease and stroke have decreased among all people, including people with diabetes.
Jonathan Pearson-Stuttard, of Imperial College London and author of the study, said: "Vascular disease accounts for about 25 per cent of all diabetes deaths, up from 43 per cent about 20 years ago.
", the leading cause of death for diabetes complications has transitioned from vascular disease to cancer.
, cancer is now the leading cause of death for people with diabetes (28 per cent of all deaths from diabetes) and the biggest factor in the mortality gap between diabetics and non-diabetics.
the reasons for this, the researchers note, are mainly related to overweight in diabetics, which is the main risk factor for cancer.
addition, the proportion of deaths attributable to dementia has increased significantly over the past 18 years, from 2 per cent of people with diabetes and 3 per cent of non-diabetics in 2011 to 16 per cent in 2018.
study also showed that 10 of the 12 related complications had a decline in mortality, with the largest absolute declines in is bloody heart disease, stroke and direct deaths from diabetes.
, however, deaths from dementia and liver disease are on the rise among people with diabetes.
addition, the study is a wake-up call that heart disease and stroke are no longer the main causes of death for people with diabetes, and that cancer, dementia and liver disease are making life more of a threat to people with diabetes.
: Pearson-Stuttard J, et al. Trends in predominant causes of death in individuals with and without diabetes in England from 2001 to 2018: an epidemiological analysis of linked primary care records. Lancet Diabetes Endocrinol. 2021 Feb 3:S2213-8587(20)30431-9. doi: 10.1016/S2213-8587 (20) 30431-9.MedSci Original Source: MedSci Original Copyright Notice: All noted on this website "Source: The text, images and audio and video materials of Metz Medicine or Source: MedSci Originals are owned by Metz Medicine and may not be reproduced by any media, website or individual without authorization, and shall be reproduced with the words "Source: Mets Medicine".
all reprinted articles on this website are for the purpose of transmitting more information and clearly indicate the source and author, and media or individuals who do not wish to be reproduced may contact us and we will delete them immediately.
at the same time reproduced content does not represent the position of this site.
leave a message here