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    Home > Active Ingredient News > Study of Nervous System > Large-scale studies have shown that people with blood type A have a higher risk of stroke before the age of 60

    Large-scale studies have shown that people with blood type A have a higher risk of stroke before the age of 60

    • Last Update: 2022-09-22
    • Source: Internet
    • Author: User
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    Written Shelton Source Lilac Academics
    There are many kinds of discussions about blood types, and some even sound very "metaphysical"
    .

    For example, people with type O blood are more attracted to mosquitoes, and people with type B blood are more likely to gain weight.
    .
    .
    In clinical studies, there have also been many studies that have found some link
    between different blood types and diseases.

    On August 31, 2022, a new study published in the journal Neurology linked a person's blood type to the risk of early stroke
    .

    The study found that people with blood type A had a higher
    risk of early-onset stroke than people with other blood types.
    The researchers meta-analyzed 48 past studies on genetic and ischemic strokes, including data
    from nearly 17,000 stroke patients and nearly 600,000 healthy controls who had never experienced a stroke.

    Among stroke patients, there are also early-onset strokes (strokes that occur before the age of 60) and late-onset strokes (strokes that occur after the age of 60).

    They studied the genetic information they collected to identify the genetic variants associated with stroke, and eventually found that early-onset stroke was associated with a region of chromosomes that contained genes
    that determine the ABO blood type.
    ABO blood type divides blood into 4 blood types
    according to the presence of antigen A and antigen B on the human red blood cell membrane.

    Only antigen A on the red blood cell membrane is A type blood, only antigen B is B type blood, and the presence of A and B anti principle is AB blood, while the red blood cells of individuals with type O blood have neither A antigen nor B antigen
    .
    The researchers then divided the participants into A, AB, B, and O blood groups
    .

    They compared the prevalence
    of these blood types in people with early-onset stroke, late-onset stroke, and stroke-
    The findings found that in patients with advanced stroke and those who had never had a stroke, the proportion of people with blood type A was higher (48%) and the proportion of blood types O (35%)
    was lower in patients with early-onset stroke.
    After adjusting for sex and other factors, the researchers found that people with blood type A had a 16 percent higher risk of early-onset stroke than people with other blood types, while people with blood type O had a 12 percent
    lower risk of developing stroke before age 60 than people with other blood types.

    At the same time, the study also found that the association of blood type with late-onset stroke was much weaker
    than the association between blood type and early-onset stroke.
    However, the researchers stress that the increase in this risk is relatively mild, and people with blood type A don't have to worry too much, nor do they have to undergo additional screening or medical tests
    based on this finding.
    Steven J.
    Kittner, author of the study, said we still don't know why blood type A carries a higher risk of stroke, which may be associated with coagulation factors such as platelets and cells within blood vessels, as well as other circulating proteins, which play a role in the development of blood clots
    .

    Previous studies have shown that people with blood type A have a slightly higher
    risk of developing blood clots in their legs.

    More research is needed to clarify the mechanism
    by which stroke risk increases in people with blood type A.
    Further reading:
    Research on the correlation between blood type and disease has emerged, involving a variety of diseases such as cancer, diabetes, and cardiovascular disease
    .
    Previously, a research paper by the Shanghai Jiao Tong/University of Pittsburgh Yuan Jianmin team titled Findings from the Shanghai Cohort Study, based on a 25-year follow-up of 18,244 Chinese men, looked at the association
    between ABO blood type and risk of all and specific cancers.

    The study found that Chinese men with B blood had a statistically significantly lower risk of gastrointestinal and bladder cancer compared to blood type A, while men with blood type AB had a higher
    risk of liver cancer.
    Behind the blood type and the risk of disease occurrence, there are many mechanisms that need to be explored to help everyone more accurately understand how the disease occurs and develops, so as to carry out targeted prevention or achieve more effective precision treatment
    .


    Thesis Link:

    1.
     https://n.
    neurology.
    org/content/early/2022/08/31/WNL.
    0000000000201006

    2.
    https://journals.
    plos.
    org/plosone/article?id = 10.
    1371/journal.
    pone.
    0184295Open
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