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    Home > Biochemistry News > Biotechnology News > Lateral Diffusion Coefficients of Raft Lipids From Pulsed Field Gradient NMR

    Lateral Diffusion Coefficients of Raft Lipids From Pulsed Field Gradient NMR

    • Last Update: 2020-12-10
    • Source: Internet
    • Author: User
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    The pulsed field gradient-nuclear magnetic resonance diffusion technique has an appreciable potential for biophysical investigationsin membrane biology, various lyotropic liquid crystals, and other complex fluid systems. In particular, topics like transportof molecules both across and within the plane of a lipid membrane can be successfully studied, as well as the formation oflipid domains and their intrinsic dynamics. The pulsed field gradient-nuclear magnetic resonance technique and the preparationof oriented samples for investigations of lipid lateral diffusion in macroscopically aligned bilayers, oriented by a goniometerprobe in the main magnetic field, are described. Some recent results illustrating the potential of the method in detectingand characterizing domain formation are also presented.
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