Latest research | Aging causes muscle loss!

Speaking of aging, there is a physiological change that is often overlooked by people, but it is closely related to the health and even lifespan of the elderly-that is, the loss of muscle.

But with the increase of age, the number and function of satellite cells will gradually decrease.

As the name suggests, stem cells can differentiate into many types of cells in our body.

A recent study published in "Stem Cell Research & Therapy" found that using a small artificial molecule called givinostat to induce stem cells to differentiate into muscle progenitor cells or muscle cells can promote muscle repair and regeneration.

The National Institutes of Health provided a grant of US$1.

01.

Picture from reference

02.

Picture from reference

Compared with human muscle progenitor cells and control muscle progenitor cells, Givinostat-induced muscle progenitor cells (Givi-MPC) have a more significant repair effect on dystrophin, and reduce muscle necrosis and muscle damage in disease model mice.

Picture from reference

More importantly, after injecting muscle progenitor cells (Givi-MPC) differentiated from stem cells, the researchers inflicted damage to the muscles of mice again.

Picture from reference

03.

Picture from reference

Aging is a common problem for mankind, and muscles are an important organ that maintains the normal operation of our body.

references:

Xuan, W.