LEPTO1: For the first time, it is shown that the B response regulator is involved in the genetic regulation at the beginning of the reduction division.

Response regulators (RRs) are involved in many biological processes, including the growth, regeneration, development, and stress response of organisms.
however, the role of response adjustment factors in the division of the minus has not been reported.
, Cheng Zhuguang, of the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, took rice as a model plant, screened infertile mutants with reduced division defects, and cloned related genes, and found that LEPTOTENE1 (LEPTO1) was involved in the formation of chromosomes in the rice minus-dividefine period.
the pollen mother cell chromosome of the LEPTO1 mutant is stuck in the pre-thin period state and cannot be further assembled into the typical fine-line chromosome state.
and sex mother cells do not have the formation of DSB, nor the number of dividing specific protein assembly, can not observe the accumulation of the cesium, and ultimately the production of pollen-free flower medicine.
LEPTO1 coding OsRR24, belongs to the B response adjustment factor, the N side has a conservative DDK and MYB domain, the C side has transcription activation activity, indicating that LEPTO1 may regulate the expression of related genes, and then regulate the formation of the chromosomes of the minus split fine line period.
related studies for the first time prove that Class B response adjustment factors are involved in the genetic regulation of the initiation of subtracted division, which provides direct evidence for further analysis of the function of response adjustment factors.
published the paper online on December 12 in The Plant Cell (DOI: 10.1105/tpc.18.00479).
Cheng Zhuguang Research Group PhD students Zhao Wei, Ren Lijun and Chen Xiaojun are the co-authors of this article, Cheng Zhuguang and Zhejiang Normal University Professor Ma Bojun as co-authors of this article.
the research was supported by the Ministry of Science and Technology, the National Natural Science Foundation of China, etc.
Source: Institute of Genetics and Developmental Biology.