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    Home > Active Ingredient News > Endocrine System > Less re-evidence! Pay attention to the new ideas of Zinlida particles to prevent and control metabolic diseases such as obesity and type 2 diabetes

    Less re-evidence! Pay attention to the new ideas of Zinlida particles to prevent and control metabolic diseases such as obesity and type 2 diabetes

    • Last Update: 2020-11-26
    • Source: Internet
    • Author: User
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    Diabetes is one of the most serious diseases threatening human health in the world today, and the number of deaths caused by diabetes is the third highest in the world, after tumors and cardiovascular disease, and the third leading killer of health! As a result, diabetes has become a major global public health problem.
    experts and scholars in the field of diabetes have been working for many years on the prevention and treatment of diabetes and the management of diabetics.
    At the 16th International Congress of Tractology and the 8th Conference on Diabetes of Chinese and Western Medicine and Vascular Diseases on October 24th, professor Jia Weiping of Guang'anmen Hospital of the Chinese Academy of Traditional Chinese Medicine, Professor Jia Weiping of the Sixth People's Hospital affiliated with Shanghai Jiaoda University, and Zhao Jiajun of Shandong Provincial Hospital Professor, Professor Yang Shuxuan of Xiamen University First Hospital, Professor Song Guangyao of Hebei Provincial People's Hospital, Professor Chen Li of Qilu Hospital of Shandong University, Professor Fang Zhaoxuan of First Hospital affiliated with Anhui University of Traditional Chinese Medicine and 11 other authoritative Chinese and Western medical experts focused on the latest developments in the field of diabetes and jointly discussed new solutions for diabetes prevention and treatment.
    chinese medicine is a new option for treating diabetes, experts say.
    Zinlida particles are based on the theory of Chinese medicine, from the "spleen" theory of the treatment of type 2 diabetes representative Chinese medicine.
    series of studies confirmed that it showed good efficacy and safety in treating type 2 diabetes, improving abnormal glucose tolerance, and weight loss.
    Professor Zhao Jiajun introduced the study of "Chinese medicine Zinlida particles improve metabolic diseases by activating BAT in mice with a high-fat diet (HFD)," and Professor Zhao said Zinlida particles can promote brown fat cell morphology formation, increase activity, significantly reduce white fat, and reduce mouse weight.
    Zhao Jiajun of Shandong Provincial Hospital, China, published the study on March 13, 2019 in the French journal Biomedicine and Drug Therapy. In the journal Pharmacotherapy, the aim is to provide new ideas and directions for the prevention and treatment of metabolic diseases such as obesity and T2DM by systematically studying the preventive effects of Zinda on HDD-induced obesity-related metabolic disorders, and by exploring the mechanisms by which Zinlida activates BAT and its associated molecular biology changes to make it produce heat to improve glycolipid metabolic disorders and insulin resistance.
    results show that Zinlida can significantly improve HFD-induced lipid metabolism disorders in obese mice, including inhibiting weight and body fat content increase, improving hyperlipidemia and glucose metabolism abnormalities, while reducing liver fat degeneration and liver inflammation. The
    study also confirmed that Zinlida can significantly increase the expression of key transcription factors in fat cell formation, increase the BAT-specific heat production gene, thereby increasing the content of mitochondrials of mature brown fat cells and their respiratory function, and further prove that Zinda activates BAT heat production mainly by improving mitochondrial biogenesic occurrence and fatty acid oxidation metabolism.
    addition, a randomized, double-blind, placebo-controlled study conducted by academician Yu Xiaolin also showed that the use of Zinlida particles combined with metformin was effective in reducing sugar and controlling symptoms, while also effectively reducing weight.
    a meta-analysis of 1810 subjects, which included 15 randomized controlled trials, showed that, in addition to significantly reducing FBG, 2hPG and HbA1c in patients with type 2 diabetes, and improving islet function, the combination of Zinlida particles was also less weight and more safe than the single use of anti-sugar drugs.
    Past studies have confirmed that Zinlida particles have multiple therapeutic effects such as protecting islet β cellular function, improving insulin resistance, regulating glycolipid metabolism, etc., and are widely used to treat type 2 diabetes and its complications, with good clinical efficacy and safety.
    Based on the effective evidence-based medical evidence and good clinical application of Zilida particle treatment type 2 diabetes, Zinlida particle has been included in the Chinese Medical Association, the World Chinese Medicine Society, the Chinese Academy of Traditional Chinese Medicine and other latest clinical guidelines, has become a representative drug for the treatment of diabetes Chinese medicine, related research won the second prize of the Chinese Academy of Traditional Chinese Medicine science and technology.
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