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    Home > Active Ingredient News > Infection > Let healthy people

    Let healthy people

    • Last Update: 2021-03-07
    • Source: Internet
    • Author: User
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    A number of foreign media reported that the British government issued a statement on the 17th local time, the country's clinical trial ethics agency has approved a new coronavirus human trial, 90 adult volunteers exposed to the new coronavirus environment, this is the world's first approved new coronavirus "human challenge test."
    understands that the trial will recruit 90 adult volunteers between the ages of 18 and 30 who have no previous history or symptoms of coronary disease, no potential health conditions, and known adverse risk factors for contracting the new coronavirus, such as heart disease, diabetes or obesity.
    These volunteers will be exposed to the new coronavirus in specialized isolation facilities, designed to help researchers understand how the human body responds to the virus, how the virus is transmitted, the minimum number of viruses needed to cause infection, etc., thus accelerating the understanding of the new corona vaccine, treatment methods, and the trial is expected to start within one month.
    Also, before conducting the trial, volunteers must pass a health risk test and undergo a 17-day quarantine before they can participate in the challenge trial, during which they are closely monitored by experts and health care providers, and the volunteers undergo two new coronavirus tests after completing the trial, and only volunteers with negative results can leave the test site.
    more than 12 months of follow-up after the trial ended, and the volunteers were not paid, but would be compensated about 4,500 pounds (about 40,000 yuan).
    the trial, which was funded by the UK government at 33.6 million pounds ($300 million), was carried out by Imperial College London, the UK government's vaccine task force and clinical trial research firm hVIVO.
    The Human Challenge Trials" help clinical researchers determine which vaccines are most likely to succeed, and allow scientists to compare the efficacy of candidate vaccines by side-by-side testing to determine which ones are more effective, according to Imperial College London.
    "Our top priority is to keep volunteers safe, and my team has safely conducted more than 10 years of human challenge research using other respiratory viruses, none of which are completely risk-free, but partners in the Human Challenge Project work to ensure that risk is minimized.
    ," says Chris Chiu, professor of infectious diseases at Imperial College London. Peter Openshaw, co-researcher of the
    Human Challenge Trials and director of the Human Challenge Alliance at Imperial College London, said: "It is by no means admpt to deliberately infect healthy volunteers with known human pathogens, and such studies are undoubtedly very helpful in identifying the mechanisms of a disease, even if it is a disease that has been studied a lot, such as neo-corona pneumonia."
    ", although in order to better understand the new crown, the study has caused great controversy, the Washington Post reported on the 17th, let healthy people infected with a potentially deadly virus, even in a controlled environment is really necessary? In response, the head of the UK's vaccine working group said: "The UK has some safe and effective vaccines, but it is vital that we continue to develop new vaccines and treatments for the new coronavirus.
    "considering that high doses of the virus can lead to serious consequences, the researchers said they would infect volunteers at the 1st possible dose, triggering virus replication with reduced symptoms."
    To date, there have been nearly 110 million confirmed cases of new crown pneumonia and more than 2.43 million deaths worldwide, including more than 27 million confirmed cases in the United States and 490,540 deaths, according to real-time data on global outbreaks at Johns Hopkins University in the United States. India was followed by India with 10950201 confirmed cases and 156,014 deaths, followed by Brazil with 997,8747 confirmed cases, followed by the United Kingdom with 408,3092 confirmed cases and more than 110,000 deaths.
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

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