Lin Hongxuan's research group reveals a new mechanism by which G protein regulates wax synthesis through calcium signaling and thus regulates heat tolerance in rice

Global warming has become a major issue threatening the world's food security.

G protein has always been a research hotspot in plant growth, development and stress response, but its molecular mechanism of heat stress tolerance has not been deeply studied; calcium signal, as a second messenger, plays an important role in the process of stress signal transduction However, there is still no plausible explanation for how calcium signals are decoded downstream of the thermal signaling pathway and transduced into physiological and biochemical responses

The research group positioned and cloned TT2from the heat-tolerant genetic resources of rice by forward genetics , which encodes a G protein γ subunit and negatively regulates the heat resistance of rice; there is a SNP in TT2 derived from tropical japonica, which makes It encodes a prematurely terminated form of the protein and acquires strong heat tolerance, while the proportion of this SNP is low in high temperature-sensitive temperate japonica rice

In summary, this study is the first to systematically link G protein regulation, calcium signal transduction and decoding, and wax metabolism pathways, and elucidate a regulatory pathway from upstream signal generation to downstream physiological and biochemical responses, which is independent of previous studies.

It is worth mentioning that during the review process of the paper, all three reviewers spoke highly of the work; in view of the importance of this work, Nature Plants published a paper written by Dr.

Kan Yi, a postdoctoral fellow at the Center for Excellence in Molecular Plant Science, Chinese Academy of Sciences, is the first author, and researcher Lin Hongxuan is the corresponding author

Paper link: https:// align="center">

The TT2 ^HPS32 locusfrom tropical japonica makes rice exhibit an obvious high temperature resistant phenotype at seedling and mature stages

　　A schematic model of the regulation of heat tolerance in rice by the TT2-SCT1/SCT2-WR2 pathway under high temperature stress