Liver Cancer: A randomized controlled study confirms no significant difference between surgery and radiofrequency ablation in patients with small hepatocellular carcinoma

For small hepatocellular carcinoma (HCC), which treatment is more effective, surgery or radiofrequency ablation (RFA), remains unclear and controversial

For small hepatocellular carcinoma (HCC), which treatment is more effective, surgery or radiofrequency ablation (RFA), remains unclear and controversial

The SURF study was a randomized controlled trial conducted at 49 centers in Japan

The SURF study was a randomized controlled trial conducted at 49 centers in Japan

During 2009-2015, 308 patients were enrolled

The median (range) follow-up period after enrollment was 5.

The median (range) follow-up period after enrollment was 5.

Differences in RFS between the two groups

The 3-year RFS rate in the surgery group was 54.

The 3-year RFS rate in the surgery group was 54.

There were 82 (54.

Two groups of recurrence patterns

Age (<60 vs >60 years), hepatitis C virus infection status, number of hepatocellular carcinoma nodules (single vs multiple), and largest hepatocellular carcinoma diameter (≤2.

Age (<60 vs >60 years), hepatitis C virus infection status, number of hepatocellular carcinoma nodules (single vs multiple), and largest hepatocellular carcinoma diameter (≤2.

Differences in stratified RFS between the two groups

In conclusion, this study shows that there is no significant difference in the efficacy of surgery and radiofrequency ablation for patients with small hepatocellular carcinoma

In conclusion, this study shows that there is no significant difference in the efficacy of surgery and radiofrequency ablation for patients with small hepatocellular carcinoma
.
The study showed that there was no significant difference in efficacy between surgery and radiofrequency ablation for patients with small hepatocellular carcinoma
.
The study showed that there was no significant difference in efficacy between surgery and radiofrequency ablation for patients with small hepatocellular carcinoma
.

Original source:

Original source:

Takayama T, Hasegawa K, Izumi N, et al.
Surgery Versus Radiofrequency Ablation for Small Hepatocellular Carcinoma: a Randomized Controlled Trial (SURF-Trial).
Liver Cancer , DOI: 10.
1159/000521665.
Published online: December 29, 2021.

Takayama T, Hasegawa K, Izumi N, et al.
Surgery Versus Radiofrequency Ablation for Small Hepatocellular Carcinoma: a Randomized Controlled Trial (SURF-Trial).
Liver Cancer , DOI: 10.
1159/000521665.
Published online: December 29, 2021.
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