Local use of vancomycin powder to reduce infection rate at surgical site

Ref: Ravikumar V,et alCurry. 2017 Jan 25doi: 10.1093/neuros/nyw127Inspinal surgery, the results of local spraying of vancomycin powder in the wound showed that the risk of surgical site infection (surgical site infection, SSI) can be significantly reducedVinod Ravikumar of Neurosurgery at Stanford University School of Medicine, USA, used vancomycin in cranial brain surgery to assess the effects on SSI, published online January 2017study included the authors' unit in the same physician's brain surgery between 2011 and 2015Between July 2011 and June 2014, 225 cases of vancomycin were not used in the control group, and 125 cases of vancomycin were used in the treatment group from June 2014 to 2015All patients are treated with standardized preventive anti-infection, i.epre- and post-operative veins are given cephalosporine sodium or cephalosporine 1g, and patients with penicillin antibiotic allergies are given vancomycin 1g intravenous dripNon-de-osteopathic valve decompression patients in the treatment group, after the bone lobe or bone lobe substitute reset spray 1g vancomycin powder; Wrap the incision with sterile dressing, change the medicine on the 2nd day after surgery, and remove the wire for 7-10 daysSSI is defined as an infection associated with craniofacial surgery, including shallow incision, deep inflammation, and meningitisA statistical analysis of SSI in two groups of patients was madethere was no statistical difference in the age, sex, history of previous cranial surgery, history of hypertension and history of diabetes in the two groups of patients in theThe treatment group had a greater proportion of glucocorticoids used in the control group, at 64.8 percent to 53.8 percent (P-0.03); SSI occurred in 5 cases (2.2%) in the control group, and the SSI rate in the treatment group was 0, and the difference between the two was statistically significant (P-0.046)In addition, patients in the treatment group did not experience side effects caused by vancomycin , the local use of vancomycin in craniofacial surgery can significantly reduce the risk of infection at the incision Therefore, the authors recommend this simple approach to preventing infection and reducing the unnecessary medical costs associated with the infection (
Feng Menglong, of Neurosurgery, Xiangnan College Hospital), editor-in-chief of "Outside The Sun Information" and Professor Chen Rongcheng , affiliated with Fudan University), review of the relevant review