Lu Yingli's team from Shanghai Jiaotong University publishes original clinical research results in international journals

Recently, Professor Lu Yingli from the Department of Endocrinology, the Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine published a titled "Long-term night shift work is associated with the risk of" in the European Heart Journal (IF 29.
98) of the European Society of Cardiology.
"atrial fibrillation and coronary heart disease" research results
.

Professor Lu Yingli, Professor Qi Lu of Tulane University, and Deputy Chief Technician Xia Fangzhen are the co-corresponding authors of this article.

In recent years, Yingli Lu’s team has been engaged in environmental (nutrition, natural, behavioral and mental environment, etc.
) and chronic diseases, especially the risk and mechanism of endocrine and metabolic disorders and cardiovascular diseases
.

This is the first large-scale prospective cohort study that explores the rhythm of life and the risk of atrial fibrillation.

The American Heart Association AHA stated that interventions on risk factors in daily life are the key to effective prevention of cardiovascular diseases such as atrial fibrillation and coronary heart disease
.

In addition to the known obesity, hypertension, diabetes, and sleep apnea syndrome, the research is dedicated to discovering new risk factors that may induce atrial fibrillation and coronary heart disease in daily activities, and focuses on the current social work.

The study included approximately 280,000 subjects with no history of cardiovascular disease in the international biobank
.

After 10 years of follow-up observation, it was found that compared with the normal population, people with “frequent or continuous nightlife and work” had the highest risk of atrial fibrillation and coronary heart disease, increasing by 12% and 22%, respectively

It is worth noting that after conducting a genetic risk assessment (GRS), it was found that whether it is a low, medium, or high atrial fibrillation genetic risk group, long-term, high-frequency nightlife and work will bring a significant increase in the occurrence of atrial fibrillation Rate
.

This result shows that the management of nightlife and work is of great guiding significance in all groups of people

In fact, the current clinical treatment of cardiovascular disease is mainly in the secondary and tertiary prevention.
The new risk factors for atrial fibrillation discovered in this study will effectively fill the gap in primary prevention of atrial fibrillation and guide the society to pay more attention to people’s daily routines.
Work and rest
.

In addition, Lu Yingli’s team recently published the latest research on SPECT-China, a well-known journal in the field of endocrinology and metabolism, Diabetologia (IF 10.
1)
.

Dr.