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    Home > Active Ingredient News > Drugs Articles > Main efficacy and function of pharmaceutical grade lanolin

    Main efficacy and function of pharmaceutical grade lanolin

    • Last Update: 2022-09-07
    • Source: Internet
    • Author: User
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     Main functions and functions of pharmaceutical grade lanolin YangmaozhiLanolin [8006-54-0] This strain is obtained by processing and refining wool
    .

    【Properties】This product is light yellow to brownish-yellow waxy substance; sticky and slippery; weak and specific odor
    .

    This product is easily soluble in tri-or medium, soluble in hot ethanol, very slightly soluble in ethanol, and insoluble in water; but it can be evenly mixed with about 2 times the amount of water
    .

    Melting point The melting point of this product (General Principle 0612 Second Method) is 36~42℃
    .

    Acid value The acid value of this product (general rule 0713) should not be greater than 1.
    5
    .

    Iodine value The iodine value of this product (general rule 0713) should be 18 to 35 (the time it should be placed in a dark place for measurement is 4 hours)
    .

    Saponification value The saponification value of this product (general rule 0713) should be 92 to 106 (the heating and refluxing time is 2 hours during measurement)
    .

    [Identification] Take 0.
    5g of this product, add 5ml to dissolve, add 1ml of acetic anhydride and 2 drops of sulfuric acid, it will turn dark green
    .

      [Check] Take 10g of this product for pH, add 50ml of water, heat and melt it on a water bath, stir continuously, let it cool, remove fat, the solution should be clear, take 10ml, add 1 drop of phenolphthalein indicator solution, it should not be red; take another 10ml, add 1 drop of methyl red indicator solution should not be red
    .

      Chloride Take 0.
    20g of this product, put it in a conical flask, add 27ml of ethanol, heat to reflux for several minutes, let it cool, add 0.
    5ml of nitric acid, filter, add 5 drops of silver nitrate ethanol solution (1→50) to the filtrate, If turbidity occurs, it should not be more concentrated (0.
    035%) compared with the control solution [take 20ml of ethanol, add 7.
    0ml of standard sodium chloride solution, 0.
    5ml of nitric acid and 5 drops of ethanolic solution of silver nitrate (1→50)]
    .

      Easily oxidized Take 10ml of the solution left over from the above pH item, add 1 drop of potassium permanganate titration solution (0.
    02mol/L), the red color should not disappear completely within 5 minutes
    .

      Insoluble matter in ethanol Take 0.
    50g of this product, add 40ml of anhydrous ethanol, boil, and the solution should be clear or slightly turbid
    .

      Weight loss on drying Take this product and dry it at 105℃ to constant weight, while stirring, the weight loss should not exceed 0.
    5% (General Rule 0831)
    .

      Residues on ignition shall not exceed 0.
    15% (General Rule 0841)
    .

      【Category】Medicinal excipients, ointment bases and emulsifiers,
    etc.

      【Storage】Sealed and kept in a cool place
    .

     
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