Make more nutritious and healthy products with precision.

. Yuan Yu Tianbo Shanghai Chengyi Food Raw Materials Co., Ltd.
health is the most valuable asset in life! However, the health status of our residents is not optimistic. China currently has 180 million people with high blood pressure, 250 million people with diabetes and prediabetes, 90 million people with hyperlipidemia and more than 70 million people with obesity, according to the State Health Planning Commission. Research shows that China's real proportion of healthy people less than 3%, the next 10 years will be a tsunami-like outbreak of chronic diseases.
Among common diseases, the influence of environmental and genetic factors
The Outline of the Healthy China 2030 Plan issued by the State Council states that industrialization, urbanization, population ageing, disease generalization, ecological environment and lifestyle changes have brought about a series of new challenges to the maintenance and promotion of health.
health is concerned not only with physical, mental and environmental health, but also with the risk factors that affect health. Environmental and genetic factors work together to influence human health. A growing body of research has found that many diseases are genetic, and environmental factors, including diet, have a huge impact on health and disease. Figure 1 reveals the relative influence of environmental and genetic factors in some common diseases.
1 Patterns of environmental and genetic factors affecting disease
there is nothing more significant than the impact of technological advances on health than the Human Genome Project. The Human Genome Project (HGP) is a multi-country, cooperative scientific project designed to determine the sequence of nucleotide base pairs that make up human DNA and to physically and functionally identify and map all genes in the human genome. This project is the world's largest bioscience collaboration. The idea of the Human Genome Project was first proposed by the United States Government in 1984, and it was officially launched in 1990 and announced in 2003. Genomics research in the 1990s pushed life science from a deep level to a new peak. The human genome is one of the most fundamental (or fundamental) principles of life science, and it is at the forefront of life science. The Human Genome Project brings opportunities and challenges to the health sector, such as precision concepts, precision medicine, and precision nutrition.
because human individuals are influenced by their genetic background, intestinal micro-ecology, eating habits and lifestyle factors, there are significant differences in the demand for nutrients and the effect of influencing substances on individuals. Therefore, on the basis of the differences of the basic characteristics of different individuals, the specific physiological state and living environment are different, accurate nutrition intervention is the correct way to prevent and treat diseases.
The emergence of precision nutrition
Precision Nutrition is a nutritional genomics, proteomics, metabolomics and other theoretical basis, combined with modern nutrition and modern medicine, a new discipline, is for the general population or sub-healthy population and even chronic diseases and other special groups of people tailored to the best nutritional health solutions, is accurate from the regulation of genes to the body's personalized nutrition intervention theory and method (see Figure 2).
2 Precision Nutrition
The range of precision nutrition covers everything from genes to cells, from tissue organs to the body as a whole. By binding to or blocking the receptors on the surface of the cell membrane, nutrients activate or inhibit the transmission of signals within cells, and regulate the expression of genes, thus affecting protein synthesis, affecting protein metabolism and cell metabolism function, and ultimately affecting the functional performance of tissue organs and even the whole body. Nutritional genomics has an important guiding role in precision nutrition. As shown in Figure 3, different genotypes have different metabolic defects. According to the metabolic characteristics of each genotype, give personalized and accurate nutrition advice. For example, a low-fat diet is recommended for people with APOE4, and a low-salt diet is recommended for people with ACED who are at risk of high blood pressure. Carriers of the MTHFR gene need dietary supplement folic acid (vitamin B9) to correct. Carriers of the APOA5 variant are closely associated with Alzheimer's disease, lipid disorders, and cardiovascular disease, and some fats should be avoided.
Figure 3 Guiding role of nutritional genomics
one-in-one, mission must reach
precision nutrition advocate - Shanghai Chengye Food Raw Materials Co., Ltd. is the first in China to put forward precision nutrition theory and develop precision nutrition products, research and development of Precision Nutrition Products NutryGeno
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series takes full advantage of the theories of modern biology, modern botany, cell biology, modern nutrition and modern medicine, rooted in the five thousand years of human solidity in China, the same origin of medicine and food Health culture as the basic concept, to Chinese medicine Yin and Yang five-line theory as a guide to the "Yellow Emperor's Inner Book" "five grains for the support, five animals for the benefit, five dishes for filling, odor and service, to complement the lean gas" as the theoretical basis, according to the body's organizational structure, for cells and the composition of intercellular physiogens, targeted selection of those ingredients clear, clear, safe and non-toxic, in clinical trials have been fully confirmed in the formulation of food ingredients.
4 Precision Nutrition Series
In the case of diabetics, high sugar, high fat and low fiber are the main causes of high blood sugar. A recent study published in cell magazine by scientists at the Weizmann Institute in Israel examining the effects of different individual traits on post-meal blood sugar found that personalized blood glucose intervention guidance based on relevant individual characteristics was significantly better than traditional blood glucose control programs. In addition, more than 100 SNPs (single nucleotide polymorphisms) associated with type 2 diabetes have been identified through the GPAS (Genome-wide Association Study) array. To date, more than 70 genes associated with type 2 diabetes have been identified by correlation analysis that affect insulin production and use. TCF7L2, for example, is a transcription factor of the Wnt signaling path, and the TCF7L2 risk allogen has been observed experimentally to cause overexaction of TCF7L2 in pancreatic beta cells. This overextending reduces insulin secretion, leading to an increased risk of type 2 diabetes and indirectly to an increase in glucose produced through the liver. Gang sugar
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Aloe Vera composite solid beverage, choose in blood sugar and prevention of diabetes complications with scientific experiments and clinical verification of the two-guarantee of new raw materials - LoesynTM Ulysses Curacao Aloe Vera Gel Powder, Insumate
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green raw technology bitter melon peptides, shell Oligosaccharides and other components, experiments have shown that it can reverse more than 700 high-fat diet-induced gene expression, including 7 related to sugar metabolism, 14 related to insulin signaling and related to fat metabolism gene expression, thereby enhancing insulin sensitivity, promoting glucose metabolism, reducing blood sugar and glycation of hemoglobin and so on (see Figure 5).Tol 5 Gang Sugar
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inhibits the overexpression of diabetes-related genes caused by a high-fat diet
Preventing disease, treating diseases, providing scientific and reasonable fine nutrition interventions for specific individuals at the right time, and preventing and controlling potential diseases, which will have a significant impact on biomedical research and traditional nutrition, and have important social and scientific significance in promoting population health and improving clinical disease status.
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