Many articles focus on the latest research results of obesity!

According to some data, there are 90 million obese people in China at present, 12 million of them are severely obese, ranking first in the world In recent years, scientists have done a lot of research in the field of obesity research In this paper, the editor will sort out the recent important research results and learn with you! Photo source: colorbox [1] neurology: obesity or poor diet and lack of exercise or no association with individuals at high risk of dementia! Doi: 10.1212/wnl.0000000000008779 recently, in a research report published in the international journal Neurology, scientists from Oxford University in the UK found that obesity in middle age is related to the higher risk of dementia in later life, but poor diet and lack of exercise are not related to the increased risk of dementia Researcher Sarah Previous studies have shown that poor diet or lack of exercise may increase an individual's risk of dementia, but our study found that these factors may not be related to the individual's long-term risk of dementia; the short-term correlation between these factors and the risk of dementia may reflect behavioral changes caused by early symptoms of dementia, such as poor diet and lack of life Move and so on The study included about 1137000 women, a quarter of whom were born in the UK between 1935 and 1950, with an average age of 56, who did not develop dementia at the start of the study The researchers asked participants about their height, weight, diet and exercise at the start of the study BMI is a measure of body size based on height and weight In this study, BMI at 20-25 is considered desirable, while more than 30 is considered obese Women who report exercising less than once a week are considered inactive At the same time, researchers calculate their calorie intake based on the daily diet reported by women 【2】 Cell metal: what's new! Glutamine may reduce obesity related inflammation doi: 10.1016/j.cmet.2019.11.019 recently, an international journal Cell In the Research Report on metabolism, researchers from institutions such as Karolin college in Sweden found that glutamine can help obese people reduce inflammation of body fat tissue and reduce body fat In this paper, researchers revealed how the level of glutamine can change gene expression in various types of cells Later researchers also need to More in-depth studies will be conducted to clarify whether glutamine supplements will be recommended as a new treatment for obesity Glutamine is an amino acid with a variety of key functions, such as providing energy for the body and maintaining good intestinal health, as well as its anti-inflammatory effect In this study, researchers collected adipose tissue from 52 obese and 29 non obese women's abdomens, revealing the different metabolic processes in these adipose tissue When the two groups of subjects In comparison, the researchers found that glutamine was the amino acid with the greatest difference between the two groups Compared with the normal weight group, the average level of glutamine in the fat tissue of obese people was lower, while the lower level of glutamine was directly related to the larger fat cell size and the higher body fat percentage, which was not related to BMI 【3】 JAMA pediatrics: obesity can affect children's brain development doi: 10.1001/jamapediatrics.2019.4708 for a long time, published research has found that there is a correlation between children's obesity and the decline of brain activity Recently, a report was published in JAMA New research in the journal Pediatrics suggests that changes in the prefrontal cortex may help explain the correlation Our results show an important link; children with higher BMI tend to have thinner cerebral cortex, especially in the prefrontal area, "the researchers said The findings are based on data retrieved from the National Institutes of Health funded research project, the adolescent brain cognitive development study, or ABCD, which tracked 10000 adolescents over a 10-year period The subjects were interviewed every two years for a series of tests, blood samples and brain scans The study analyzed the results of 3190 9 - and 10-year-olds recruited in 21 ABCD locations in 2017 According to the ranking test, subjects with higher BMI tended to have lower working memory 【4】 Nature: revealing pgrmc2 protein is helpful to develop a new method to treat metabolic diseases such as obesity and diabetes Doi: 10.1038/s41586-019-1774-2, a signal protein called pgrmc2 (progesterone receptor component 2), has not been widely studied in the past It is found in the uterus, the liver, and several other parts of the body Now, in a new study, researchers from the Scripps Institute in the United States found that the protein is abundant in fat tissue, especially in brown fat, which converts food into calories to maintain body temperature This opens the door to a new understanding of obesity and metabolism Their findings may also lead to new ways to treat obesity and many other underlying diseases, the results of which have recently been published in the journal Nature The new study by researchers Saez and his team builds on their recent discovery that pgrmc2 binds to and releases an essential molecule called heme By using biochemical techniques and advanced measurement methods in cells, Saez and his team found that pgrmc2 is the "companion" of heme, wrapping the molecule up and removing it from the cell mitochondria (cells Where heme is produced) is transported to the nucleus, where it helps perform important functions In the absence of this protective partner, heme reacts with all the molecules in its transport pathway and suffers damage 【5】 BDJ: inflammation or the node connecting periodontal disease and obesity doi: 10.1038/s41415-019-0611-1 in the United States, obesity and periodontal disease are the most common non communicable diseases Some studies believe that there is a certain correlation between these chronic diseases Recently, an international journal published in British Dental In the journal's research report, scientists from the University of Case Western Reserve and other institutions analyzed the impact of obesity on non-surgical periodontal care through research, and evaluated the possibility of a link between obesity and periodontal disease The relationship between obesity and periodontal disease is not a simple causal relationship, on the contrary, these diseases have something in common, that is, inflammation; through the analysis of a large number of existing studies, researchers found that the current data show that the increase of body mass index, waist circumference and body fat percentage are directly related to the increase of periodontal disease risk of individuals, and most of the studies are at a certain time Point to analyze population groups, rather than study the same population in a longer time range Photo source: cc0 public domain [6] PLoS Med: overthrow the existing cognition! Caesarean section does not increase the risk of obesity in offspring! Doi: 10.1371/journal.pmed.1002996 recently, scientists from Karolin college in Sweden found that compared with women who have a normal birth, the offspring of women who have a caesarean section may not be likely to suffer from obesity The relevant research results are published in the international journal PLoS On medicine, the findings contradict those of several smaller studies that have previously revealed the link between caesarean section and obesity in offspring, but did not consider a large number of maternal and prenatal factors, which were analyzed in this study In recent years, caesarean section is very popular among pregnant women, with the rate rising from 6.7% in 1990 to 19.1% in 2014 The rise of caesarean section population has aroused the attention of scientists The researchers aim to clarify the long-term impact of caesarean section on the health of future generations, some of which have found that caesarean section will increase the asthma of future generations , multiple allergies and obesity risks However, the research conclusions of the relationship between caesarean section and obesity risk of offspring are only obtained in some small studies, which can not explain a large number of possible confounding factors, and can not distinguish different types of caesarean section 【7】 Obility reviews: gut microbes are the key factor to cause childhood obesity doi: 10.1111/obr.12963 recently, scientists from Wake Forest Baptist Health published a review that suggested that gut bacteria and their interactions with immune cells and metabolic organs (including adipose tissue) play a key role in childhood obesity We have long believed that obesity is the result of too many calories, the researchers said However, a series of studies over the past decade have confirmed that microbes in our intestines may be one of the causes of obesity According to data from the Centers for Disease Control and prevention, the percentage of children and adolescents affected by obesity in the United States has more than tripled since the 1970s The article points out that among the school-age children, obesity is increasing at a rate of 2.3% every year, which indicates that the health prospects of the next generation are worrying 【8】 Food Chem toxi: can coffee beans alleviate obesity? Doi: 10.1016/j.fct.2019.110672 recently, an international magazine food and chemical In the report on toxicology, scientists from the University of Michigan found that when water-soluble extracts from the epidermis of coffee beans were used to treat mouse adipocytes, two phenolic compounds (protocatechuic acid and gallic acid) contained in them could reduce adipoinflammation, improve glucose absorption and insulin sensitivity The results show that eating these bioactive compounds as part of the diet can be expected to be a strategy to prevent obesity related chronic diseases (such as type II diabetes and cardiovascular disease) We have studied the bioactive compounds in different foods and seen their benefits in the prevention of chronic diseases, the researchers said In this study, the researchers studied the effects of two types of cells, macrophages and fat cells, as well as the mixture of compounds and individual phenols in the extract on the production and metabolism of fat cells in vivo and the sensitivity of related hormones In addition, they also studied their effects on the inflammatory response 【9】 Int J Epidemiol: lose weight quickly! Obesity before age 40 significantly increases the risk of multiple cancers! Doi: 10.1093/ije/dyz188 recently, in a research report published in the International Journal of epidemiology, scientists from the University of Bergen wanted to find out how overweight (BMI over 25) and obesity (BMI over 30) in adults increased the risk of different types of cancer Obesity is an established risk factor for several cancers In this study, we focused on the degree, time and duration of overweight and obesity and the risk of cancer Over time, obesity increases the risk of disease In this study, the researchers included two or more measurements, with a time interval of at least three years In addition, in this study, the