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Botox, or Botox or Botox, is a neurotoxin protein produced by Botox during reproduction, which can no longer transmit signals to muscles to achieve muscle relaxation or even muscle paralysis by preventing nerve endings from reabsorbing acetylcholine, mainly to treat overactive muscles.
botulinum toxin is one of the most toxic natural substances and one of the most toxic proteins in the world, generally requiring only a very small dose during treatment.
in the field of medical beauty, the main applications of botulinum toxin are muscle spasms and wrinkle removal, the injection effect is generally maintained for 3-6 months, after the recurrence of wrinkles and muscle enlargement can be re-injected.
are divided into A, B, Ca, Cb, D, E, F, G eight types, according to its toxicity and antigen, the current medical and aesthetic industry is widely used in the A-type injectable botulinum toxin. there are only three countries in the world
that can produce Botox for beauty: the United States, the United Kingdom and China.
about 10 botulinum toxin brands listed worldwide, the best-selling botox of Allergan, has been approved by 83 countries over the past 20 years, and according to its annual report, Baoto's global sales for 2019 were $991.3 million, up 9.3 percent from 2018.
only two NMPA-approved products in China, namely Heng and Elgen of the Lanzhou Institute of Biological Products, were sino-biotech shares.
Hengli was listed in 1993, but was approved for medical beauty in 2009, only for the end price of 2000-3000 yuan;
China's botulinum toxin market has been growing at a high rate in recent years, with more beautiful and new oxygen releases showing that botulinum toxin projects have ranked second in the most popular medical beauty program for three consecutive years since 2016.
the volume of Hengli sales accounted for more than 70% of the domestic market, sales and baotol equivalent, the current Chinese botulinum toxin market annual total sales of about 150 million yuan.
1. The higher threshold of botulinum toxin belongs to the biological agent, has a strong neurotoxicity, the production process of its production process determines the characteristics of the product.
but local companies are also laying out china's botulinum toxin market, Huaxi Bio in 2015 with South Korea's Medytox set up a joint venture Medybloom holding 50% of each, responsible for the development and expansion of the injectable botulinum toxin market;
2. The market is not regulated China has long existed botulinum toxin black market, the product is mainly smuggled into South Korea powder, white, green and some fake botulinum toxin, because of its relatively cheap and are in some irregular beauty salons to inject.
Botox needs to be kept, distributed, registered, and Botox injection surgery has certain risks, must be carried out by medical lyson with medical qualifications, the general beauty salon does not have this ability, the probability of adverse safety accidents is higher.
improper use of injectable botulinum toxin may cause muscle relaxation paralysis and, in severe cases, life-threatening health symptoms such as respiratory failure and heart failure.
as regulation increases, the market becomes more regulated.
since 2017, the Food and Drug Administration and the Public Security Bureau of the provinces and cities of the country have stepped up their efforts to crack down on the botulinum toxin market, cracked several cases of the preparation and sale of botulinum toxin counterfeit drugs, and in 2019 the seven departments jointly launched a nationwide illegal medical and beauty supervision operation.
.