Medicinal grade anhydrous calcium dibasic phosphate cas7757-93-9 use

Pharmaceutical grade anhydrous dibasic calcium phosphate cas7757-93-9 use of dibasic calcium phosphate, is an inorganic compound, the chemical formula is CaHPO4, is a white crystalline powder, easily soluble in dilute hydrochloric acid, dilute nitric acid, acetic acid, slightly soluble in water, insoluble in ethanol, mainly used as a food additive
.

Appearance: white crystalline powder solubility: soluble in dilute hydrochloric acid, dilute nitric acid, acetic acid, slightly soluble in water, insoluble in ethanol [check] chloride Take 0.
20g of this product, add 10ml of water and nitric acid 2ml, slowly heat until dissolved, cool, check according to law (General 0801), compared with the control liquid made of standard sodium chloride solution 10.
0ml, it shall not be more concentrated (0.
05%)
.

Sulfate Take 1.
0g of this product, add a small amount of dilute hydrochloric acid, so that it can be dissolved, dilute to 100ml with water, shake well, filter, take 20ml of filtrate, add 5ml of water, check according to law (General 0802), and compare with the control liquid made of standard potassium sulfate solution 4.
0ml, it shall not be more concentrated (0.
2%)
.

Fluoride Plastic utensils
are used in operation.

Take about 2.
0g of this product, weigh precisely, place in a 100ml measuring bottle, add 20ml of water and 2.
0ml of hydrochloric acid, shake to dissolve, add buffer (take sodium citrate 73.
5g, add water 250ml to dissolve, that is, obtain) 50ml, dilute with water to the scale, shake well, as a test solution; another precision weigh the sodium fluoride 221mg dried at 105 ° C for 4 hours, put it in a 100ml measuring bottle, add water to dissolve, add buffer 50.
0ml, dilute with water to the scale, shake well, that is, get fluorine standard storage liquid (each 1ml is equivalent to 1mg of F), precision take the appropriate amount , quantitatively diluted with buffer to make a solution containing F 0.
1 μg, 0.
2 μg, 0.
5 μg, 1.
0 μg per 1 ml as a control solution
.

The electrode indicated by the fluorine ion selective electrode and the saturated calomel electrode are measured by the reference electrode, and the potential response value (mV)
of the above control solution and the test solution are measured respectively.

Taking the logarithmic value (IgC) of the fluorine ion concentration (μg/ml) as the x-axis, and the potential response value as the y-axis, the standard curve is drawn, and the fluoride ion concentration in the test solution is determined from the standard curve according to the potential value of the test solution, and the fluoride content shall not exceed 0.
005%.
Carbonate Take 1.
0g of this product, add 5ml of water, mix well, add 2ml of hydrochloric acid, do not boil
.

Insoluble substances in hydrochloric acid Take about 5.
0g of this product, precision weighing, add 10ml of hydrochloric acid and 40ml of water, dissolve by heating, dilute to 100ml with water, if there is an insoluble substance, filtered, the filter residue is washed with water, until the reaction of the lotion does not show chloride, dry at 105 ° C for 1 hour, the residual residue shall not exceed 5mg
.

Blazing weight loss Take about 1.
0g of this product, precision weighing, burn to constant weight at 800 °C, the weight reduction should be 6.
6% ~ 8.
5%.
Barium salt Take 0.
50g of this product, add 10ml of water, heat, add hydrochloric acid drops, stir with drops, dissolve, filter, add potassium sulfate test solution to the filtrate, and turbidity
must not occur within 10 minutes.

Iron salt Take 2.
5g of this product, dilute 20ml of hydrochloric acid, heat to dissolve, dilute to 50ml with water, take 1.
0ml, check according to law (General Rule 0807), and compare with the control liquid made of standard iron solution 2.
0ml, not deeper (0.
04%)
.

Lead salt take about 0.
2g of this product, precision weighing, placed in a 50ml measuring flask, dissolved and diluted to a scale with nitric acid solution (1→100), shake well, as a test solution; take another standard lead solution (equivalent to 10μg of Pb per 1ml) in an appropriate amount, and dilute it with nitric acid solution (1→100) to make a solution containing 0ng, 10ng, 20ng, 30ng, 40ng, 50ng per 1ml, as a
。
According to the atomic absorption spectrophotometry (general rule 0406 first method), the graphite furnace as the atomizer, measured at a wavelength of 283.
3nm, calculated, the lead content shall not exceed 0.
0005%.
Arsenic salt Take 1.
0g of this product, add 5ml of hydrochloric acid and 23ml of water to dissolve, check according to law (General 0822 First Law), should comply with the provisions (0.
0002%)
.