Medicinal grade sodium alginate viscosity 500 sample filled with 500 g binder

Medicinal grade sodium alginate viscosity 500 sample filled with 500 g binder 1, the molecular formula constituting sodium alginate: C6H7NaO6, mainly composed of sodium salt of alginic acid, consisting of β-D- mannonic acid (M unit) and α-L-guluoglucuronic acid (G unit) by β-1,4-glycosidic bonds and composed of different proportions of GM, MM and GG fragments of the copolymer
.

2, the molecular weight of sodium alginate for molecular weight commodities is usually like polysaccharides, relatively dispersed
.

Therefore, the molecular weight of one sodium alginate usually represents the average
of all molecules in this group.

Common ways of expressing molecular weights are numerical average molecular weight (Mn) and heavy average molecular weight (Mw
).

In a polydisperse molecular group, usually Mw > Mn
.

The coefficient of Mw/Mn is the dispersion index, and the index of sodium alginate commodities is classically ranged from 1.
5 to 2.
5
.

The commonly used method of determining molecular weight is calculated based on the determination of
intrinsic viscosity and light scattering.

3, the molecular formula formula is C6H9NaO7, the molecular structure is shown in Figure 14, the pH value of sodium alginate is slightly soluble in water, insoluble in most organic solvents
.

It is soluble in an alkaline solution, making the solution viscous
.

Sodium alginate powder becomes wet when exposed to water, and the hydration of particles makes its surface viscous
.

The particles then quickly bond together to form clumps, which slowly fully hydrate and dissolve
.

If the water contains other compounds that compete for hydration with alginate, sodium alginate is more difficult to dissolve in water
.

Sugar, starch or protein in water will reduce the hydration rate of sodium alginate, and the mixing time needs to be extended
.

Monovalent cationic salts, such as NaCl, have a similar effect
at concentrations above 0.
5%.

The pH of sodium alginate in a 1% distilled aqueous solution is about 7.
2
.

5.
Stability sodium alginate has hygroscopicity, and the amount of moisture contained in the balance depends on the relative humidity
.

Dried sodium alginate is stored fairly stable in a well-sealed container at temperatures of 25°C and below
.

Sodium alginate solution is stable
at pH 5 to 9.

The degree of polymerization (DP) and molecular weight are directly related to the viscosity of sodium alginate solution, and the reduction of viscosity during storage can be used to estimate the degree
of sodium alginate depolymerization.

Sodium alginate with high polymerization is not as stable as sodium
alginate with low polymerization.

Sodium alginate is reported to be hydrolyzed by proton, which depends on time, pH and temperature
.

Propylene glycol alginate solution is stable at room temperature and pH 3~4; When the pH is less than 2 or greater than 6, the viscosity decreases quickly even at room temperature