Medicinal value of Gardenia / instructions of Gardenia Jinhua pill / parameters of small water pill machine

Gardenia: also known as Yellow Gardenia, gardenia, white toad, is the fruit of gardenia, a plant of Rubiaceae At present, gardenia fruit is a traditional Chinese medicine, which is the first batch of dual-use medicine and food resources issued by the Ministry of health It has the functions of liver protection, cholestasis, blood pressure reduction, sedation, hemostasis, detumescence and so on It is commonly used in the clinical treatment of jaundice hepatitis, sprain and contusion, hypertension, diabetes and so on [scientific name] Gardenia jasminoides Ellis [English name] cape jasmine [alias] Gardenia jasminoides, bougainvillea and white toad [classification] Rubiaceae, gardenia [form] evergreen shrub, up to 2m high Leaves opposite or 3-whorled, leathery, oblong or obovate lanceolate, 5-14cm long, 2-7cm wide, entire; stipules 2-piece, usually connected with synthetic tube-shaped surrounding branchlets Flowers solitary at the branch or leaf axil, white, fragrant; calyx green, cylindric; corolla high footed saucer, lobes 5 or more; ovary inferior The flowering period is from May to July, and the fruiting period is from August to November [variety] cultivated variety of Gardenia grandiflora Nakai, with large double petals and no fruit The leaves of Gardenia ovalifolia Nakai are obovate with round apex Var angustifolia Nakai is a wild Gardenia with narrow leaves Variegated Gardenia var aureo variegata Nakai [habits and distribution] it likes warm and humid climate, good sunlight but can not withstand strong sunlight It is suitable to grow in loose, fertile, well drained, light viscous acid soil, and is a typical acid flower Most parts of the country are cultivated There are wild areas in the south, which are located in Jiangxi, Hubei, Hunan, Zhejiang, Fujian and Sichuan Chinese herbal medicine [scientific name of Chinese herbal medicine] Frutus Gardeniae [English name] cape jasmine fruit [alias] Gardenia jasminoides Ellis, Huangguoshu, Gardenia jasminoides and hongzhizi [original] this product is the dry and mature fruit of Rubiaceae Gardenia jasminoides Ellis, a dicotyledonous plant, whose root can also be used as medicine [collection and storage] from September to November, when the fruit ripens and turns red and yellow, remove the stem and impurities, steam it to steam or put it in boiling water and heat it slightly, take it out and dry it The roots are dug in summer and autumn, washed and dried Place in a ventilated and dry place [preparation] Gardenia: remove impurities and grind Stir fry Gardenia: take the pure gardenia, stir fry according to the clear fry method until it is yellowish brown [character] the product is long oval or oval, 1.5-3.5cm in length and 1-1.5cm in diameter The surface is reddish yellow or brownish red, with 6 winged longitudinal edges, and there is usually one obvious longitudinal vein between the edges, with branches Sepals remaining at the top, base slightly pointed, with residual fruiting pedicels The pericarp is thin and brittle, with a slight luster; the inner surface is light and glossy, with 2-3 raised false diaphragms The seeds are mostly oblate and ovoid, agglomerated into clusters, dark red or red yellow, with dense verrucous processes on the surface It's slightly sour and bitter [chemical composition] it contains geniposide, gardenoside, shanzhiside, gardoside, geniposide acid, gardenin, crocin-1, CRO Cetin, scandoside methyl ester, etc [identification] (1) this product is reddish brown powder The pericarp stone cells are oblong in shape; the pericarp fibers are long and thin, fusiform, about 10 μ m in diameter, and about 110 μ m in length, which are often crisscross and obliquely inlaid; the crystalline stone cells are round or polygonal, 17-31 μ m in diameter, with thick walls and 8 μ M in diameter The stone cells of testa are yellow or light brown, long polygonal, rectangular or irregular in shape, 60-112 μ m in diameter, 230 μ m in length, with thick walls, large pits and brownish red cavities The diameter of calcium oxalate clusters is 19-34 μ M (2) take 0.2g powder of the product, add 5ml water, heat in water bath for 3min, and filter Take 5 drops of filtrate, put it in an evaporating dish, evaporate it to dryness, add 1 drop of sulfuric acid, it will turn blue-green, turn brown rapidly, and then turn purple brown (3) take 1g of this product powder, add 10ml of 75% ethanol, soak it in a warm water bath for 2 hours, filter it, and use the filtrate as the test solution In addition, take the gardenoside reference, add ethanol to make a solution containing 4mg per 1ml as the reference solution According to the test of thin layer chromatography (Appendix Ⅵ b), take 5 μ l of each of the above two solutions, and place them on the same silica gel G thin layer plate respectively Take ethyl acetate acetone formic acid water (5:5:1:1) as the developing agent, develop them, take them out, dry them in the air, spray them with sulfuric acid ethanol (5 → 10) solution, and heat them at 110 ℃ until the spots are clear In the chromatogram of the test article, the spots of the same color are displayed at the corresponding positions of the chromatogram of the reference article Chemical constituents of traditional Chinese medicine [1] the fruit contains iridoids: gardenoside, geniposide, genipin-1-geniobioside, shanzhiide, Gardo side, scandoside methyl ester, geniposide Acid), deacetyl aspartic acid, methyl deacetyl asparosidate, 10 acetylgeniposide 6 "- p-coumaroyl geniposide" Droxy-3-metal) glutaroyl Quinic acid, 3,4-dicaffeoyl-5 - (3-hydroxy-3-methylglutaryl) quinic acid, CRO Cetin, ursolic acid, crocin glucoside, etc It also contains flavonoids: rutin, D-Mannitol, β - sitosterol, choline, nonacosane, xanthophyll, etc The pericarp and seeds also contain geniposide, juezin, juezinic acid and juezin gentiopicroside The flowers contain triterpenoids: gardenic acid A, B and gardenic acid The leaves contain gardenoside, jueside, cerbinal, methyl dihydrojasmonate, limonene, linalool, etc The content of D-Mannitol, oleanolic acid and lentisterol in rhizome were determined by liquid chromatography (Appendix Ⅵ d) In the experiment of chromatographic conditions and system suitability, octadecylsilane bonded silica gel was used as filler, acetonitrile water (15:85) as mobile phase, and the detection wavelength was 238nm The number of theoretical plates should be no less than 1500 according to the peak of gardenoside The preparation of the control solution precisely weigh a proper amount of gardenoside control, add methanol to make a solution containing 30 μ g per 1ml Preparation of test solution take 0.1g powder of this product [meanwhile take another powder of this product to measure water content (Appendix IX H *Method), precisely weigh, place in a conical flask with stopper, precisely add 25ml of methanol, close the stopper, weigh, ultrasonic treatment for 20 minutes, cool down, then weigh, use methanol to make up the weight lost, shake, filter, precisely measure 10ml of continuous filtrate, place in a 25ml measuring flask, add methanol to the scale, shake well, and then obtain The determination method is to precisely suck 10 μ l each of the reference solution and the test solution, inject them into the liquid chromatograph, and determine them The content of gardenoside (c17h24o10) in this product shall not be less than 1.8% according to the calculation of dried product [sex, taste and classics] bitter, cold Return to the heart, lung and sanjiaojing [function indications] fruit: purgative fire, remove irritation, clear heat and diuresis, cool blood and detoxify It is used for the treatment of fever, upset, jaundice, hematuria, blood drenching and astringent pain, hematemesis, red eye swelling and pain, fire and poison sores, and external pain Root: purgative fire, detoxify, clear away heat and dampness, cool blood and remove blood stasis It is used for infectious hepatitis, bruise, wind and fire toothache [usage and dosage] 6-9g Appropriate amount of external raw products, and adjust the application at the end of research One to two roots [remarks] (1) it is used for fever, upset and restless Gardenia is good at catharsis and relieving heat In the early stage of exogenous fever, there are fever, chest distress, upset and other symptoms Gardenia and Douchi can be used to penetrate pathogenic factors, relieve heat, remove anxiety and depression In case of high fever, dysphoria, delirium and other diseases due to all febrile diseases, this product can be used with Coptis and other diarrhea to clear pathogenic heat (2) it can be used for hematemesis, epistaxis, hematuria, redness of eyes, swelling of sores, etc Gardenia jasminoides Ellis also has the functions of cooling blood, hemostasis, clearing away heat and detoxifying It is often used to treat blood fever and misbehaving It is often compatible with Shengdi, Platycladus orientalis, Cortex Moutan, etc.; it can be used to treat red swelling pain of the eyes, and it can be compatible with chrysanthemum, stone cassia, etc.; it can be used to treat sore and swelling toxin, and it can be used equally with Coptis, honeysuckle and forsythia (3) this product can also relieve heat and promote dampness It can be used for jaundice, yellowing of skin, fatigue, diet reduction and other diseases caused by damp heat depression and Jie It is often the same as Phellodendron chinense and Artemisia scoparia It can also be used to reduce swelling and activate collaterals It can be used for falling injury, sprain and bruise, skin bruise and pain It is a commonly used "tendon medicine" in the folk, especially for the injury of muscles and tendons near the joints of limbs (4) Gardenia jasminoides Ellis, a famous gardenia, is light, clear and uplifted It can relieve the lung fire, remove the heat from the skin, and relieve the external and internal heat It can also relieve the three scorching fire, cool the blood, clear the heart and heat It can be used for the heat disease and upset, the blood fever and the hot urine Therefore, gardenia can not only clear air and heat, but also clear blood and heat As for heat and dampness relieving, it can be used to treat jaundice, which is also its specialty With Scutellaria, this product can relieve lung fire; with light Douchi, it can relieve the heat inside and outside; with Scutellaria, it can relieve the heat inside and outside; with Shengdi, Danpi, it can cool the blood and stop bleeding; it can cure the blood heat and rash, spit the blood; with Phellodendron, Yinchen, it can clear the heat and dampness, and treat the damp heat and jaundice In the past, the clinical application of Gardenia jasminoides Ellis (Gardenia jasminoides Ellis) has been simplified in Shanghai The whole gardenia is used instead of Gardenia jasminoides Ellis (Gardenia jasminoides Ellis) skin and gardenia kernel Gardenia Jinhua pill [drug name] trade name: Gardenia Jinhua pill Chinese Pinyin: Zhizi Jinhua Wan [ingredients] gardenia, honeysuckle, Scutellaria, phellodendron, rhubarb, Coptis, Anemarrhena, smallpox [sexual] this product is a yellow to yellow brown water pill with bitter taste [action category] this product is a kind of over-the-counter medicine with real fire syndrome [function indications] clear away heat and fire, cool blood and detoxify It is used for hyperactivity of lung and stomach, sore mouth and tongue, swelling and pain of gums, dizziness of red eyes, swelling and pain of throat, and defecation secret knot [usage and dosage] take orally, 9g (1 bag) at a time, once a day [precautions] 1 Avoid smoking, alcohol, spicy and greasy food 2 Patients with chronic diseases such as heart disease, liver disease, diabetes and kidney disease should be treated in the hospital