Men are more dangerous!

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Introduction: Re-analysis of REWIND research data, diabetes-related cardiovascular disease, men are at greater risk! At the recent European Association for the Study of Diabetes (EASD) annual meeting, Ferrannini, a scholar from Karolinska Institutet in Sweden, brought a new research result.
The research showed that in high cardiovascular risk people or people with confirmed cardiovascular disease There are obvious gender differences in cardiovascular outcomes among people with diseases
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Giulia Ferrannini's post-mortem analysis of the REWIND trial The investigator performed post-mortem analysis on the data of some participants in the REWIND clinical trial
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The Cox proportional hazards model was used to analyze the differences in the risk of cardiovascular outcomes between women and men, including fatal/non-fatal stroke, fatal/non-fatal myocardial infarction, cardiovascular death, all-cause mortality, and hospitalization for heart failure
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The incidence of cardiovascular events: males are higher than the 9,901 females included in the study (46.
3% of females).
Among the study participants with type 2 diabetes with high risk of cardiovascular disease or confirmed cardiovascular disease, significantly fewer women have a history of cardiovascular disease In males (20.
0% vs.
41.
4%; P<0.
001)
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However, the proportion of women reaching cardiovascular treatment goals (such as blood pressure, blood lipids) is lower than that of men.
Nevertheless, the analysis results show that: ➤In the population with a history of CVD at baseline, female MACE composite outcome, lethal/non-lethal myocardium The incidence of infarction is significantly lower than that of men
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➤In the population without a history of CVD at baseline, the incidence of MACE composite outcome, fatal/non-fatal myocardial infarction, CV death, all-cause death, and heart failure hospitalization events in women was significantly lower than that in men
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Figure 1 Comparison of the risk of adverse cardiovascular events between men and women in the high cardiovascular risk/cardiovascular disease population In other words, women are less likely to achieve CV risk management treatment goals than men
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Nevertheless, with the exception of stroke, the risk of adverse CV outcomes for women is significantly lower than that for men
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This gender difference is worthy of further study
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