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The United Kingdom has approved the listing of Recarbrio (Aamine Pernam/Sestatin/Rebatan, imipenem/cilastatin/relebactam) for the treatment of adult patients with limited options for hypoxic Glyan negative bacteria infection.
this program uses MSD's aminine/sestatin in combination with a new endamidease inhibitor, relebactam, which is designed to restore the sensitivity of drug-resistant strains to acetaminophen.
: At least 700,000 people worldwide die each year from drug-resistant infections, according to the World Health Organization .
the urgent need for new therapies to address the growing occurrence of antimicrobial resistance (AMR), few pharmaceutical companies are willing to do research in this area.
reality is that whenever new antibiotics are introduced, they are usually retained until the end and are used only to treat the most resistant infections.
the development of a new drug typically takes 10 to 12 years and costs more than $1 billion, the lack of a timely return on investment has led many drugmakers to abandon antibiotic research and development.
to fight AMR and promote timely returns on research funding, 20 biopharmaceutical companies recently launched a $1 billion AMR Action Fund.
AMR Action Fund plans to bring two to four new antibiotics to patients by 2030.
, managing director of MSD in the UK and Ireland, said: "The world risks losing its most powerful tool in medicine: antibiotics.
unless we act immediately, AMR, as an imminent threat, could affect us all in the future, with even greater impact on public health and the economy than COVID-19.
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