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"Mermaids" help find multiple sclerosis medications

 Last Update: 2022-10-02
 Source: Internet
 Author: User

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Both zebrafish and humans have GPR17 receptors

Zebrafish should be well known to many aquarium lovers, mainly because of its amazing pigmentation

"For example, at the University of Bonn, we are studying how zebrafish can repair defective neural tissue,"

The genes of fish are replaced by human genes

"So we took a different approach,"

The researchers demonstrated in their preliminary study of the so-called GPR17 receptor that this substitution is effective

Immature state

In multiple sclerosis, however, the body's own immune system destroys the myelin layer

"Zebrafish also have GPR17 receptors," explains Dr.

In the process of finding new active ingredients, the substance is first tested

Humanized zebrafish as a tractable tool for in vivo evaluation of pro-myelinating drugs

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