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    Home > Chemicals Industry > Chemical Technology > Metabolism and Toxicology of Benzimidazole Drugs

    Metabolism and Toxicology of Benzimidazole Drugs

    • Last Update: 2021-10-11
    • Source: Internet
    • Author: User
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    17.


    17.


    Studying the pharmacokinetics of BMZs antiparasitic drugs is of great significance for determining its drug activity


    Oral administration of thiabendazole is easily absorbed in the intestine.


    Experiments have shown that the metabolism and residues of different BMZs in different types of animals and different tissues are very different


    Losifidou et al


    17.


    Although BMZs are broad-spectrum, high-efficiency, and low-toxicity antiparasitic drugs, unreasonable use of drugs can also cause serious adverse reactions.


    BMZs within 20-30 times of the recommended dose are considered safe, and it is difficult to produce acute toxicity


    Animal experiments have proved that some BMZs have certain embryo toxicity and teratogenic effects


    BMZs can also cause adverse reactions in animals


    Abuse of BMZs may cause parasites to develop drug resistance


    Related Links: Uses of Benzimidazole Drugs

     

     

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