-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Serum uric acid (SUA) was associated with short-term blood sugar in healthy subjects, and prospective epidemiological studies have shown that elevated SUA is associated with an increased risk of type 2 diabetes.
whether SUA independence is associated with a higher risk of post-transplant diabetes (PTDM) in kidney transplant recipients (KTR) is unclear.
recently, researchers conducted a longitudinal cohort study of 524 adult KTRs recruited during their college years (2008-2011) who were normally functioning and ≥1 years old, according to a recent study published in Metabolism-Clinical and Test, an authoritative journal in the field of metabolic diseases.
researchers conducted a multivariate, adjusted Cox proportional risk regression analysis to assess the association between time-updated SUA and PTDM (as defined by the American Diabetes Association's diagnostic criteria).
SUA average (SD) at the baseline is 0.43 (0.11) mmol/L.
52 (10%) KTRs had PTDM during follow-up periods of 5.3 years (IQR 4.1-6.0).
in a single-factor forward-looking analysis, SUA was associated with an increased risk of PTDM (1.75 for each additional SD, 1.36-2.26 for 95% CI; P.lt;0.001).
After adjusting for metabolic syndrome, lifestyle, estimated glophrocyte filtration rates, immunosuppressive therapy, cytocytovirus and hepatitis C virus infections, the results remained essentially the same (HR 1.89, 95% CI 1.32-2.70; P=0.001).
these results are consistent in classification analysis, robust in sensitivity analysis, and have no outlier values.
, it can be seen that in KTR, the higher SUA level and PTDM risk increase have a strong correlation.
the results of the study are consistent with evidence supporting SUA as a new independent risk marker for type 2 diabetes.
。