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1.
Science: The results of the release of vaccines to strengthen the protection of primates.
The top academic journal Science published a research paper on the new coronavirus vaccine, which provides new evidence for the vaccine to strengthen the prevention of mutated new coronaviruses
.
This preclinical study showed that six months after the macaque was vaccinated with the new crown vaccine mRNA-1273, the third dose of the mRNA vaccine can enhance the animal's antibody response, especially the neutralizing activity of the antibody against the mutant virus
.
The researchers pointed out that the booster needle induced a strong immune memory response and potentially longer-lasting immunity
.
2.
With the new use of the old drug, Masitinib can reduce the viral load of the new coronavirus by 99% in just 6 days.
On July 20, 2021, researchers from the University of Chicago and other institutions published a titled: Masitinib is a broad in the top international academic journal Science.
Coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 (masitinib is a broad coronavirus 3CL inhibitor that can block the replication of SARS-CoV-2) research paper
.
The research team used the strategy of "new use of old drugs".
The research team screened a library of 1900 drugs that have been used safely and found that 20 drugs can effectively inhibit the replication of the new coronavirus in in vitro experiments
.
Among them, masitinib (masitinib) is the most effective, which is an oral tyrosine kinase inhibitor that can competitively inhibit the activity of the main protease of the new coronavirus, 3CLpro, thereby inhibiting the replication of the new coronavirus
.
In vivo experiments in mice showed that Masitinib treatment can reduce the titers of the new coronavirus in the lungs and nose of mice to less than 1% of the original, and lung inflammation has also been reduced in just 6 days
.
In addition, Masitinib is equally effective against new crown α, β, and γ mutants in in vitro experiments
.
3.
No entry but no exit, all staff Nucleic Acids Beijing Chaoyang District Tomorrow First City No.
6 Yard implemented temporary control and control Beijing Chaoyang District Liqing Road First Community Neighborhood Committee issued a notice: Due to the epidemic, Liqing Road First Community Tomorrow First City No.
1 and No.
3 buildings of the No.
6 community will be temporarily controlled from 14:30 on October 28, 2021
.
4.
212 people from Shanghai to Beijing South were quarantined in Jinan for 14 times Close contacts of 212 people from Shanghai to Beijing South on the G14 high-speed rail were in Jinan for centralized isolation and medical observation
.
Science: The results of the release of vaccines to strengthen the protection of primates.
The top academic journal Science published a research paper on the new coronavirus vaccine, which provides new evidence for the vaccine to strengthen the prevention of mutated new coronaviruses
.
This preclinical study showed that six months after the macaque was vaccinated with the new crown vaccine mRNA-1273, the third dose of the mRNA vaccine can enhance the animal's antibody response, especially the neutralizing activity of the antibody against the mutant virus
.
The researchers pointed out that the booster needle induced a strong immune memory response and potentially longer-lasting immunity
.
2.
With the new use of the old drug, Masitinib can reduce the viral load of the new coronavirus by 99% in just 6 days.
On July 20, 2021, researchers from the University of Chicago and other institutions published a titled: Masitinib is a broad in the top international academic journal Science.
Coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 (masitinib is a broad coronavirus 3CL inhibitor that can block the replication of SARS-CoV-2) research paper
.
The research team used the strategy of "new use of old drugs".
The research team screened a library of 1900 drugs that have been used safely and found that 20 drugs can effectively inhibit the replication of the new coronavirus in in vitro experiments
.
Among them, masitinib (masitinib) is the most effective, which is an oral tyrosine kinase inhibitor that can competitively inhibit the activity of the main protease of the new coronavirus, 3CLpro, thereby inhibiting the replication of the new coronavirus
.
In vivo experiments in mice showed that Masitinib treatment can reduce the titers of the new coronavirus in the lungs and nose of mice to less than 1% of the original, and lung inflammation has also been reduced in just 6 days
.
In addition, Masitinib is equally effective against new crown α, β, and γ mutants in in vitro experiments
.
3.
No entry but no exit, all staff Nucleic Acids Beijing Chaoyang District Tomorrow First City No.
6 Yard implemented temporary control and control Beijing Chaoyang District Liqing Road First Community Neighborhood Committee issued a notice: Due to the epidemic, Liqing Road First Community Tomorrow First City No.
1 and No.
3 buildings of the No.
6 community will be temporarily controlled from 14:30 on October 28, 2021
.
4.
212 people from Shanghai to Beijing South were quarantined in Jinan for 14 times Close contacts of 212 people from Shanghai to Beijing South on the G14 high-speed rail were in Jinan for centralized isolation and medical observation
.
