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Pay attention to your body even for small problems!
Executive Summary
On October 24, 2022, a study published in Frontiers in Cardiovascular Medicine showed that mild thyroid disease can cause serious heart problems
.
Screenshot of the review
status quo
for major adverse cardiovascular events.
However, the condition of mild thyroid dysfunction remains unclear
.
Dr.
Johannes Dietrich, Associate Professor at the Clinic of St.
Joseph's Hospital Bochum, Germany, said:
- Although in some studies, elevated minimum levels of thyroid hormones, even high normal concentrations within the reference range for healthy people, predicted an increased risk of sudden cardiac death, other studies did not show this association
.
Therefore, until recently, the jury
was inconclusive as to whether to treat patients with subclinical hyperthyroidism and hypothyroidism.
conclusion
To better understand, the international team conducted a new evidence-based study that analyzed the results
of 32 studies on the subject.
In the evaluation of meta-analyses, the researchers found that both subclinical hypothyroidism and subclinical hyperthyroidism can predict the risk of
cardiovascular death.
It is worth mentioning that serum free thyroid hormone T4 (FT4) concentrations are directly associated
with cardiogenic death and other adverse cardiovascular events.
Dr.
Johannes Dietrich, Associate Professor at the Clinic of the Ruhr University Bochum (RUB) Clinic, said:
- The results showed that cardiovascular risk continued to increase with increasing FT4 concentrations, and there was a complex U-type risk relationship with the control hormone thyroid-stimulating hormone (TSH) concentrations
In one form ("dysregulated type"), primary thyroid disease directly increases the concentration of thyroid hormones, thereby increasing the risk of
cardiovascular disease.
In another form ("homeostasis"), genetic factors, chronic stress, and psychological stress are involved in the regulation between the pituitary gland and the thyroid gland, so indirectly elevated FT4 concentrations also promote arrhythmias
.
prospect
Johannes Dietrich, Associate Professor at the Clinic of the Ruhr University Bochum (RUB) Clinic, said:
- This has built a new building block for our understanding of the link between the thyroid and heart and may pave the way
for personalized preventive care. - In addition, thyroid function may be a biomarker of pathogenesis in patients with arrhythmias, helping to tailor optimized drug regimens
.
Review debut: EurekAlert!
Media Contact：
Meike Driessen
Ruhr-University Bochum
meike.
driessen@uv.
rub.
de
Office: 49-234-32-26952
DOI：10.
3389/fcvm.
2022.
942971
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