Military Medical Research Institute: In vivo virus mutation and immune response characteristics in persistent new coronavirus infection

During the new crown epidemic, persistent infections for several months frequently occurred in young patients with COVID-19, often with mild or asymptomatic symptoms, and with persistently positive nucleic acid tests

The researchers successively collected a group of nasopharyngeal swabs from patients with new crown infections.

Genome sequencing analysis showed that the infected person mainly carried the new coronavirus B.

The results of viral RT-PCR monitoring showed that the Ct value of ORF1ab gene in 6 patients with persistent infection all rose to above 35 85 days after the first positive detection, and 5 of them rose to above 35 after 60 days

The researchers continued to analyze the immune response of people with persistent infection with the new coronavirus

Original link: https:// of Prof.

research direction

Infectious Disease Epidemiology; Space Epidemiology; Biosafety

Social work

Convener of the Public Health and Preventive Medicine Group of the Academic Degrees Committee of the State Council, member of the National Biosafety Expert Committee, member of the National Expert Advisory Committee on Public Health Emergencies, Expert of the National Expert Advisory Group on Prevention and Handling of Bioterrorist Attacks, and China Health and Quarantine Expert Committee Expert, member of the National Animal Epidemic Prevention Expert Committee; Expert of the National Key Research and Development Program "Biosafety Key Technology Research and Development" Key Special Expert Group; Executive Director of the Chinese Preventive Medicine Association, Deputy Director of the Chinese Preventive Medicine Association Health Emergency Professional Committee, and Epidemiology Professional Committee Standing committee member; vice chairman of the Health Geographic Information Professional Committee of the Chinese Society of Health Information; chief scientist of the National Defense Science and Technology Innovation Special Zone Subject Expert Group; chairman of the military biohazard prevention medical professional committee and director of the military biosafety expert committee

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