Molecular Psychiatry: Drinking coffee for a long time may change the functional connection of the brain!

Coffee is one of the most popular beverages in the world.
Drinking in the United States is even higher than tap water.
In China, coffee has even become a daily life-saving water for workers
.

However, coffee can refresh the brain and resist drowsiness in the short-term, but long-term drinking may have a negative effect on the brain's nerves

Coffee is one of the most popular beverages in the world.

Recently, researchers from the University of Minho in Portugal discovered that regular coffee consumption has an impact on the human brain network and is closely related to the frequency of drinking
.

This is the first study on the effects of long-term coffee consumption on the brain network, and the results were published in the journal Molecular Psychiatry .

Recently, researchers from the University of Minho in Portugal discovered that regular coffee consumption has an impact on the human brain network, and it is closely related to the frequency of drinking

In this study, researchers used social media, emails and Portuguese newspapers to publish the recruitment of subjects.

A total of 56 subjects were recruited and divided into habitual coffee drinkers (CD) and non-coffee drinkers.
(NCD)

In this study, researchers used social media, emails and Portuguese newspapers to publish the recruitment of subjects.

The researchers collected the coffee drinking habits of the subjects through interviews, and assessed their depression, anxiety and stress through the Depression, Anxiety and Stress Scale (DASS-21) .
Then came the MRI scan phase.
After the first scan of the NCD group, 50 mL of coffee was drunk , and another round of examinations was performed 30 minutes later .
Finally, MRI data analysis is carried out through independent component analysis, network-based statistical analysis and dominant eigenvector dynamics analysis .

The results showed that in the neuroimaging assessment, independent component analysis showed that the somatosensory network and the edge network function connection of the CD group in the resting state were significantly reduced
.

At the same time, the CD group also showed reduced functional connectivity in a network that included subcortical and posterior brain areas related to somatosensory, motor, and emotional processing as assessed by network-based statistics

The results showed that in the neuroimaging assessment, independent component analysis showed that the somatosensory network and the edge network function connection of the CD group in the resting state were significantly reduced

The more coffee you drink, the worse the FC drop .

The more coffee you drink, the worse the FC drop .

The study further showed that the CD group showed a longer life span for functional networks involving subcortical areas, visual networks, and cerebellum
.

Importantly, all these differences depended on the frequency of caffeine intake and recurred after drinking coffee in the NCD group

Further studies show , , CD group showed a longer life under cortical regions involved in visual function of the network of networks, and the cerebellum

The thalamus, cerebellum, right central posterior gyrus, left central anterior gyrus, bilateral caudate nucleus and putamen are most affected by coffee .

The thalamus, cerebellum, right central posterior gyrus, left central anterior gyrus, bilateral caudate nucleus and putamen are most affected by coffee .

In addition, the CD group showed a higher stress level than the NCD group.
Although no other group effects were observed in this psychological evaluation, the increase in caffeine intake frequency was also related to the increase in male anxiety
.

In addition, the CD group showed a higher stress level than the NCD group.
Although no other group effects were observed in this psychological evaluation, the increase in caffeine intake frequency was also related to the increase in male anxiety
.

In conclusion, this study shows that long-term coffee drinking may change the functional connections of the brain, and higher coffee / caffeine intake can lead to increased stress and anxiety
.

In summary, this study shows that long-term coffee drinking may change brain functional connections.
Higher coffee.
In short, this study shows that long-term coffee drinking may change brain functional connections.
Higher coffee / caffeine intake can cause stress and Anxiety increases
.
/ Caffeine intake can lead to increased stress and anxiety
.

Original source

Original source

Magalhães R, Picó-Pérez M, Esteves M, et al.
Habitual coffee drinkers display a distinct pattern of brain functional connectivity .
Mol Psychiatry.
2021;10.
1038/s41380-021-01075-4.
doi:10.
1038/s41380-021-01075 -4.

Magalhães R, Picó-Pérez M, Esteves M, et al.
Habitual coffee drinkers display a distinct pattern of brain functional connectivity .
Mol Psychiatry.
2021;10.
1038/s41380-021-01075-4.
doi:10.
1038/s41380-021-01075 -4.
Habitual Coffee Drinkers Run the display A DISTINCT pattern of Brain Functional Connectivity in this message