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More than 370,000 people followed up for 9 years: drinking tea to prevent dementia is true, and it can reduce the risk by 29%!

 Last Update: 2022-08-12
 Source: Internet
 Author: User

participant characteristics

At baseline, the study included a total of 377,592 subjects from the primary care dataset (Figure 1) with a mean age of 549 years (SD 83); 204,980 (53%) were fema.

The relationship between tea consumption and dementia

There was a significant association between tea consumption and a reduced risk of developing dementia after controlling for age, gender and ethnicity (Model

Model 1, HR = 823 (95% CI: 751-902) 1-2 cups/day, HR = 792 (95% CI: 727-862) 3-4 cups/day, HR = 803 (95% CI: 803 (95%CI:95%CI:803) 732–880) 5–6 cups/day;

Model 2, HR = 857 (95% CI: 767–959) for 1–2 cups/day, HR = 801 (95% CI: 721–890) for 5–6 cups/day, 3–6 cups/day HR = 859 (95% CI: 769–96

However, there was no significant difference in dementia risk between individuals who drank more than 6 cups of tea per day and those who did not drink tea, as follows:

Model 1, HR = 910 (95% CI: 802-032) 7–8 cups/day, HR = 952 (95% CI: 817-108) ≥ 9 cups/day;

Model 2, HR = 891 (95%CI: 766–037) for 7–8 cups/day, HR = 946 (95%CI: 788–136) for ≥9 cups/d.

Results of subgroup analyses stratified by age showed that, in middle age, tea consumption was significantly associated with a reduced risk of dementia in both models, and in the fully adjusted model, in individuals with 1-6 cups per day of tea consumption The incidence of dementia is reduced by approximately 17-2

Results of subgroup analyses stratified by sex showed that women who drank 3-4 cups of tea per day were less likely to develop dementia in both models (HR = 800 [95% CI: 687–933.

Results of subgroup analyses stratified by form of dementia (AD/VD) showed that in Model 1, consumption of 1–6 cups per day was associated with a lower incidence of .

Nonlinear relationship between tea consumption and dementia

In Figure 4, the researchers modeled and visualized the association of tea consumption with dement.

After adjusting for all covariates, the risk of developing dementia decreased significantly until it bottomed out around 3 cups/day, and increased thereafter ( P for non-linearity = 7E − ⁰⁴.

At 3 cups/day, the HR for dementia was 943 per cup (95% CI: 907-981), indicating an approximately 6% lower risk of an extra cup per d.

A similar U-shaped relationship was observed in middle age, with dementia risk lowest at about 3 cups of tea per day (P for non-linearity = 8E − ⁰⁴.

No nonlinear relationship was observed in later li.

Nonlinear relationships were observed in both females and mal.

The largest reduction in dementia incidence was associated with intake of approximately 3 cups per day in women ( P for non-linearity = 006,) and 3–6 cups per day in men ( P for non-linearity = 02
In addition, U-shaped associations of tea consumption with AD and VD were also shown, and the largest reduction in both incidences was associated with tea consumption of 2 to 3 cups per day (AD: P for non-linearity = 046; VD: Pfor non- linear = 01

In conclusion, using data from 377 592 individuals from the UKB, this study investigated the association between tea consumption and dementia during a 9-year follow-up peri.

Results showed that moderate tea drinkers (1–6 cups/day) were less likely to develop ACD, AD and VD after adjusting for covariat.

Another major finding was a U-shaped association between tea consumption and dementia risk, with optimal intake of approximately 3 cups per d.

These findings suggest that tea consumption, as a potentially modifiable life&g.

This research will provide a relatively simple and low-cost solution to interventions for age-related cognitive decline or dement.

Original source:

Hu HY, Wu BS, Ou YN, et .

Tea consumption and risk of incident dementia: A prospective cohort study of 377 592 UK Biobank participan.

Transl Psychiatr.

2022;12(1):17 Published 2022 Apr 2 doi: 11038/s41398-022-01923-z

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