Mother's cholesterol levels during pregnancy are related to the severity of heart attacks in adult offspring

A small study showed that mothers’ high cholesterol during pregnancy is associated with more serious heart attacks in young adult offspring

The author of the study, Dr.

"More research is needed to verify our findings," he continued

This retrospective study included 310 patients who were hospitalized between 1991 and 2019

The average age of 89 heart disease patients was 47 years old, and 84% of them were men

The cholesterol level of pregnant women during pregnancy is significantly correlated with the severity of each heart attack (number of blood vessels, ejection fraction, CK and CK-mb)

After adjusting the number of age, gender, body mass index (BMI), cardiovascular risk factors (obesity, smoking, high blood pressure, family history of heart disease or high cholesterol, diabetes, angina pectoris), the researchers analyzed the pregnant women's cholesterol levels during pregnancy The relationship with the severity of a heart attack

Pregnant women's cholesterol during pregnancy can independently predict the severity of heart attack, and the ratio of the ratio with age, gender, BMI, number of risk factors, and serum cholesterol after hospitalization was 1.

In the second analysis that included all 310 patients, the researchers examined the relationship between maternal cholesterol levels during pregnancy and atherosclerosis in adult offspring

Even after adjusting for age, gender, and cardiovascular risk factors, pregnant women’s cholesterol levels are still significantly correlated with two atherosclerosis risk indicators

Dr.

He concluded: "Prospective studies are needed to better assess the degree of the influence of mother's cholesterol on the development of atherosclerosis in the offspring, as well as the comprehensive impact of risk factors throughout life

DOI

10.